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Keratoderma, Palmoplantar, Diffuse

Known as: Syndrome, Unna-Thost, Keratosis Palmaris et Plantaris, Thost Unna Syndrome 
An autosomal dominant disorder characterized by a widely distributed, well-demarcated hyperkeratosis of the palms and soles. There is more than one… 
National Institutes of Health

Related topics

Related topics

23 relations
Bone callusHyperkeratosisIn BloodIntegumentary system

Narrower (3)

Diffuse palmoplantar keratoderma, Bothnian typeHyperkeratosis of the palms and soles and esophageal papillomasPALMOPLANTAR KERATODERMA, NONEPIDERMOLYTIC

Broader (1)

Skin callus

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2008
Review
2008
Genetics of Gastroesophageal Cancer: Paradigms, Paradoxes, and Prognostic Utility
Hereditary diffuse gastric cancer and tylosis are autosomal dominant cancer susceptibility syndromes. Accumulating evidence also… 
2002
2002
Characterization of a 500 kb region on 17q25 and the exclusion of candidate genes as the familial Tylosis Oesophageal Cancer (TOC) locus
The locus for a syndrome of focal palmoplantar keratoderma (Tylosis) associated with squamous cell oesophageal cancer (TOC) has… 
2001
2001
Identification of DMC1, a novel gene in the TOC region on 17q25.1 that shows loss of expression in multiple human cancers
AbstractFrequent allelic losses within chromosomal band 17q25.1 in a variety of human cancers have suggested the presence of one… 
1997
1997
TYLOSES AND THE MAINTENANCE OF TRANSPIRATION
Abstract During a study of transpiration and embolism-formation in petioles of sunflower, tyloses were frequently observed in… 
Review
1988
Review
1988
Factors associated with cancer of the oesophagus: an overview.
The incidence pattern of oesophageal cancer varies across the world with roughly a 500-fold difference in rates (truncated… 
1984
1984
Screening diagnosis and staging of esophageal cancer.
In geographic areas where there is a high risk of esophageal cancer, analysis of cells obtained from the esophagus has been used… 
1982
1982
Diffuse palmoplantar keratoderma with deafness.
Two brothers with diffuse palmoplantar keratoderma (Thost-Unna type) also were deaf. Of the 38 members of the patients' family… 
1975
1975
NEUROICHTHYOSIS WITH HYPOGONADSSM (RUD'S SYNDROME)
ABSTRACT: Rud's syndrome is a neuroichthyosis with hypogonadism, associated with mental deficiency and epilepsy. Short stature is… 
1974
1974
Oral leukoplakia associated with tylosis and esophageal carcinoma.
The association between tylosis (palmoplantar keratoderma) and esophageal carcinoma in a group of related patients has been… 
1960
1960
Simplified acid orcein and Giemsa technique for routine staining of skin sections.
The normal and pathological skin presents a variety of tissue elements that are not demonstrated or not easily differentiated in… 
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