C. Lightdale

Publications370
h-index57
Citations13,732
Highly Influential Citations346
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Photodynamic therapy with porfimer sodium for ablation of high-grade dysplasia in Barrett's esophagus: international, partially blinded, randomized phase III trial.
BACKGROUND Barrett's esophagus (BE) may lead to high-grade dysplasia (HGD) and adenocarcinoma. The objective was to examine the impact of treating patients with BE and with HGD by using porfimer… Expand
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Bile acid and inflammation activate gastric cardia stem cells in a mouse model of Barrett-like metaplasia.
Esophageal adenocarcinoma (EAC) arises from Barrett esophagus (BE), intestinal-like columnar metaplasia linked to reflux esophagitis. In a transgenic mouse model of BE, esophageal overexpression of… Expand
  • 292
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Radiofrequency ablation in Barrett's esophagus with dysplasia.
BACKGROUND Barrett's esophagus, a condition of intestinal metaplasia of the esophagus, is associated with an increased risk of esophageal adenocarcinoma. We assessed whether endoscopic radiofrequency… Expand
  • 763
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Five-year efficacy and safety of photodynamic therapy with Photofrin in Barrett's high-grade dysplasia.
BACKGROUND Barrett's esophagus (BE) with high-grade dysplasia (HGD) is a risk factor for development of esophageal carcinoma. Photodynamic therapy (PDT) with Photofrin (PHO) has been used to… Expand
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Preoperative staging of gastric cancer: comparison of endoscopic US and dynamic CT.
Fifty consecutive patients with gastric adenocarcinoma proved by means of biopsy underwent preoperative staging with endoscopic ultrasonography (US). Dynamic computed tomography (CT) of the chest and… Expand
  • 270
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Endoscopic radiofrequency ablation for Barrett's esophagus: 5-year outcomes from a prospective multicenter trial.
BACKGROUND AND STUDY AIMS The AIM-II Trial included patients with nondysplastic Barrett's esophagus (NDBE) treated with radiofrequency ablation (RFA). Complete eradication of NDBE (complete… Expand
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  • PDF
Localization of pancreatic endocrine tumors by endoscopic ultrasonography.
BACKGROUND After a pancreatic endocrine tumor has been diagnosed on the basis of clinical signs and the results of laboratory tests, localization of the tumor by the usual imaging procedures fails in… Expand
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Durability of radiofrequency ablation in Barrett's esophagus with dysplasia.
BACKGROUND & AIMS Radiofrequency ablation (RFA) can eradicate dysplasia and intestinal metaplasia in patients with dysplastic Barrett's esophagus (BE), and reduce rates of esophageal adenocarcinoma.… Expand
  • 377
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  • PDF
Balloon-based, circumferential, endoscopic radiofrequency ablation of Barrett's esophagus: 1-year follow-up of 100 patients.
OBJECTIVE To assess the dose-response, safety, and efficacy of circumferential endoscopic ablation of Barrett's esophagus (BE) by using an endoscopic balloon-based ablation device (HALO360 System).… Expand
  • 289
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Endoscopic ablation of Barrett's esophagus: a multicenter study with 2.5-year follow-up.
BACKGROUND For patients with Barrett's esophagus (BE), life-long surveillance endoscopy is recommended because of an elevated risk for developing dysplasia and esophageal adenocarcinoma. Various… Expand
  • 188
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