Hyperkeratosis

Known as: hyperkeratoses, Thickening of stratum corneum, Thickened stratum corneum 
A condition marked by thickening of the outer layer of the skin, which is made of keratin (a tough, protective protein). It can result from normal… (More)
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
BACKGROUND Previously, a study of ours showed that the combination of dabrafenib and trametinib improves progression-free… (More)
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Review
2009
Review
2009
Interest in sebaceous gland physiology and its diseases is rapidly increasing. We provide a summarized update of the current… (More)
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Highly Cited
2007
Highly Cited
2007
The interleukin (IL)-1 family members IL-1alpha, -1beta, and -18 are potent inflammatory cytokines whose activities are dependent… (More)
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Highly Cited
2006
Highly Cited
2006
R-spondins are a recently characterized small family of growth factors. Here we show that human R-spondin1 (RSPO1) is the gene… (More)
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Review
2004
Review
2004
Aging of skin is a continuous process that may be enhanced by sun exposure. Photoaging may provoke changes different from aging… (More)
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Highly Cited
2003
Highly Cited
2003
Transcription factor Nrf2 (encoded by Nfe2l2) regulates a battery of detoxifying and antioxidant genes, and Keap1 represses Nrf2… (More)
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Review
1996
Review
1996
The papillomavirus family represents a remarkably heterogeneous group of viruses. At present, 77 distinct genotypes have been… (More)
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1994
1994
BACKGROUND AND DESIGN Epidermolytic hyperkeratosis (EHK) is a rare autosomal dominant disorder of cornification. While different… (More)
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Highly Cited
1990
Highly Cited
1990
The promoter region of the suprabasal keratin 10 gene has been used to direct expression of a mutant human Harvey-ras oncogene to… (More)
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Highly Cited
1984
Highly Cited
1984
Two hundred fifty-seven patients with oral leukoplakia were studied and followed for an average period of 7.2 years. All lesions… (More)
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