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Label-retaining cells reside in the bulge area of pilosebaceous unit: Implications for follicular stem cells, hair cycle, and skin carcinogenesis
Involvement of Follicular Stem Cells in Forming Not Only the Follicle but Also the Epidermis
Existence of slow-cycling limbal epithelial basal cells that can be preferentially stimulated to proliferate: Implications on epithelial stem cells
Strategies of epithelial repair: modulation of stem cell and transit amplifying cell proliferation.
Three strategies of epithelial repair are demonstrated: stem cell replication, the unleashing of additional rounds of cell proliferation that remain as an untapped reserve under normal circumstances, and enhancement of TA cell proliferation via a shortening of the cycling time.
MicroRNAs of the mammalian eye display distinct and overlapping tissue specificity.
The tissue and cell specificity of ocular miRNAs suggests that these noncoding RNAs may be regulating aspects of development and differentiation.
Reaction of mast cell proteases tryptase and chymase with protease activated receptors (PARs) on keratinocytes and fibroblasts
The results suggest that the proteases tryptase and chymase secreted from mast cells in skin may affect the behavior of surrounding cells by the hydrolysis of PARs expressed by these cells.
Ocular surface epithelia contain ABCG2-dependent side population cells exhibiting features associated with stem cells
- M. Budak, O. Alpdogan, Mingyuan Zhou, R. Lavker, M. Akinci, J. Wolosin
- BiologyJournal of Cell Science
- 15 April 2005
SP cells were characterized by extremely low light side scattering and contained a high percentage of cells that showed slow cycling prior to tissue collection; exhibited an initial delay in proliferation after culturing; and displayed clonogenic capacity and resistance to phorbol-induced differentiation; all features consistent with a stem cell phenotype.
Desmoglein 3 anchors telogen hair in the follicle.
Epidermal stem cells: properties, markers, and location.
Like stem cells of other tissues, epidermal stem cells are important because they not only play a central role in homeostasis and wound repair, but also represent a major target of tumor initiation and gene therapy.
Hair follicle stem cells.
One of the main concepts to emerge from this workshop is that follicular epithelial stem cells are multipotent, capable of giving rise not only to all the cell types of the hair, but also to the epidermis and the sebaceous gland.