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Karyopherins

Known as: Karyopherins [Chemical/Ingredient], Transportin, Transportins 
A family of proteins involved in NUCLEOCYTOPLASMIC TRANSPORT. Karyopherins are heteromeric molecules composed two major types of components, ALPHA… 
National Institutes of Health

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ExportinsHASTY protein, ArabidopsisImportinsXpo4 protein, mouse
In BloodProcess of secretionTNPO1 geneagonists

Papers overview

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2012
2012
Identification of Residues in the C-terminal Domain of HIV-1 Integrase That Mediate Binding to the Transportin-SR2 Protein*
Background: The molecular details of the TRN-SR2/HIV-1 IN interaction are not known. Results: Crucial amino acids in IN for the… 
2011
2011
Nuclear transporters in a multinucleated organism: functional and localization analyses in Aspergillus nidulans
In this first functional and localization analysis of the nuclear transport machinery in a multinucleated cell, reverse genetic… 
2010
2010
Transportin 3 and importin α are required for effective nuclear import of HIV-1 integrase in virus-infected cells
Unlike other retroviruses, Human immunodeficiency virus type-1 (HIV-1) can infect terminally differentiated cells, due to the… 
2007
2007
Conformational heterogeneity of karyopherin beta2 is segmental.
Karyopherinbeta2 (Kap beta2) or transportin imports numerous RNA binding proteins into the nucleus. Kap beta2 binds substrates in… 
2003
2003
Karyopherin-Mediated Nuclear Import of the Homing Endonuclease VMA1-Derived Endonuclease Is Required for Self-Propagation of the Coding Region
ABSTRACT VMA1-derived endonuclease (VDE), a site-specific endonuclease in Saccharomyces cerevisiae, enters the nucleus to… 
2002
2002
The molecular mechanism of translocation through the nuclear pore complex is highly conserved.
In this report we investigated the activity of vertebrate nuclear transport factors in a primitive organism, Amoeba proteus, to… 
Highly Cited
2002
Highly Cited
2002
Identification of the Nucleocytoplasmic Shuttling Sequence of Heterogeneous Nuclear Ribonucleoprotein D-like Protein JKTBP and Its Interaction with mRNA*
JKTBP proteins are related to a family of heterogeneous nuclear ribonucleoproteins (hnRNPs) that function in mRNA biogenesis and… 
Highly Cited
1998
Highly Cited
1998
Functional Conservation of the Transportin Nuclear Import Pathway in Divergent Organisms
ABSTRACT Human transportin1 (hTRN1) is the nuclear import receptor for a group of pre-mRNA/mRNA-binding proteins (heterogeneous… 
Highly Cited
1998
Highly Cited
1998
Nuclear Import and the Evolution of a Multifunctional RNA-binding Protein
La (SS-B) is a highly expressed protein that is able to bind 3′-oligouridylate and other common RNA sequence/structural motifs… 
Highly Cited
1997
Highly Cited
1997
A Nuclear Import Pathway for a Protein Involved in tRNA Maturation
A limited number of transport factors, or karyopherins, ferry particular substrates between the cytoplasm and nucleoplasm. We… 
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