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KT 5823

Known as: 9,12-Epoxy-1H-diindolo(1,2,3-fg:3',2',1'-kl)pyrrolo(3,4-i)(1,6)benzodiazocine-10-carboxylic acid, 2,3,9,10,11,12-hexahydro-10-methoxy-2,9-dimethyl-1-oxo-, methyl ester, (9R-(9alpha,10beta,12alpha))-, KT-5823, KT5823 
National Institutes of Health

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2 relations

Broader (2)

CarbazolesProtein Kinase Inhibitors

Papers overview

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Highly Cited
2007
Highly Cited
2007
Effects of manipulating the nitric oxide/cyclic GMP pathway on bovine oocyte meiotic resumption in vitro.
Highly Cited
2004
Highly Cited
2004
Cyclic GMP-dependent neurite outgrowth by genipin and nerve growth factor in PC12h cells.
Highly Cited
2002
Highly Cited
2002
Hemin induces neuroglobin expression in neural cells.
Neuroglobin is a newly identified vertebrate globin that binds O(2) and is expressed in cerebral neurons. We found recently that… 
2002
2002
Expression of atrial natriuretic peptide receptor-A antagonizes the mitogen-activated protein kinases (Erk2 and P38MAPK) in cultured human vascular smooth muscle cells
To understand the signaling mechanisms of atrial natriuretic peptide (ANP) receptor-A (NPRA), we studied the effect of the ANP… 
2001
2001
Nitric Oxide Signaling Pathway Regulates Potassium Chloride Cotransporter-1 mRNA Expression in Vascular Smooth Muscle Cells*
Rat vascular smooth muscle cells (VSMCs) express at least two mRNAs for K-Cl cotransporters (KCC): KCC1 and KCC3. cGMP-dependent… 
Highly Cited
2000
Highly Cited
2000
Calcium channel activation facilitated by nitric oxide in retinal ganglion cells.
We investigated the modulation of voltage-gated Ca channels by nitric oxide (NO) in isolated salamander retinal ganglion cells… 
Highly Cited
1999
Highly Cited
1999
Inhibition of spinal protein kinase C reduces nerve injury-induced tactile allodynia in neuropathic rats
Highly Cited
1994
Highly Cited
1994
Prostaglandin E2 and prostacyclin inhibit the production and secretion of endothelin from cultured endothelial cells.
Endothelin-1 (ET-1) is the most potent endogenous vasoconstrictor yet identified. This peptide plays an important role in the… 
Highly Cited
1994
Highly Cited
1994
Apoptosis of vascular smooth muscle cells. Protein kinase C and oncoprotein Bcl-2 are involved in regulation of apoptosis in non-transformed rat vascular smooth muscle cells.
We examined the effect of several inhibitors/activators of various protein kinases on the proliferation and apoptosis of… 
Highly Cited
1994
Highly Cited
1994
Induction of early-response genes KC and JE by mycobacterial lipoarabinomannans: regulation of KC expression in murine macrophages by Lsh/Ity/Bcg (candidate Nramp)
The murine chromosome 1 gene Lsh/Ity/Bcg (candidate Nramp) regulates macrophage activation for antimicrobial activity against… 
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