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KMUP 1

Known as: KMUP-1, KMUP1 cpd 
 
National Institutes of Health

Papers overview

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2010
2010
Background and purpose:  KMUP‐1 is known to increase cGMP, enhance endothelial nitric oxide synthase (eNOS) and suppress Rho… Expand
2010
2010
Aging populations with neurodegenerative disorders will gradually become a greater problem for society. Serum deprivation-induced… Expand
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2010
2010
  • J. Yeh, J. Hsu, +6 authors J. Wu
  • British journal of pharmacology
  • 2010
  • Corpus ID: 31946915
Background and purpose:  To determine whether KMUP‐1, a novel xanthine‐based derivative, attenuates isoprenaline (ISO)‐induced… Expand
2010
2010
AIMS This study investigates the actions of KMUP-1 on RhoA/Rho-kinase (ROCK)-dependent Ca(2+) sensitization and the K(+)-channel… Expand
2007
2007
Soluble guanylyl cyclase (sGC)/cyclic guanosine monophosphate (cGMP)/protein kinase G (PKG) and Rho kinase (ROCK2) pathways are… Expand
2006
2006
In the study of anti-proinflammation by 7-[2-[4-(2-chlorobenzene)piperazinyl] ethyl]-1,3-dimethylxanthine (KMUP-1) and 7-[2-[4-(4… Expand
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2005
2005
This study investigated whether KMUP‐1, a synthetic xanthine‐based derivative, augments the delayed‐rectifier potassium (KDR)‐ or… Expand
2004
2004
7‐[2‐[4‐(2‐chlorophenyl)piperazinyl]ethyl]‐1,3‐dimethylxanthine (KMUP‐1) produces tracheal relaxation, intracellular accumulation… Expand
2002
2002
In isolated endothelium‐intact or denuded rabbit corpus cavernosum preconstricted with phenylephrine, KMUP‐1 (0.001 – 10 μM… Expand
2001
2001
KMUP‐1 (1, 3, 5 mg kg−1, i.v.), a xanthine derivative, produced dose‐dependent sustained hypotensive and short‐acting… Expand