KMT2C gene

Known as: LYSINE-SPECIFIC METHYLTRANSFERASE 2C, KMT2C, MLL3 
This gene plays a role in both methylation and transcriptional regulation
National Institutes of Health

Papers overview

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2015
2015
Acute myeloid leukemia (AML) with an FLT3 internal tandem duplication (FLT3-ITD) mutation is an aggressive hematologic malignancy… (More)
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Highly Cited
2014
Highly Cited
2014
Oesophageal cancer is one of the most aggressive cancers and is the sixth leading cause of cancer death worldwide. Approximately… (More)
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Highly Cited
2014
Highly Cited
2014
Esophageal squamous cell carcinoma (ESCC) is one of the deadliest cancers. We performed exome sequencing on 113 tumor-normal… (More)
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Highly Cited
2014
Highly Cited
2014
PURPOSE Aggressive cutaneous squamous cell carcinoma (cSCC) is often a disfiguring and lethal disease. Very little is currently… (More)
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Highly Cited
2013
Highly Cited
2013
Enhancers play a central role in cell-type-specific gene expression and are marked by H3K4me1/2. Active enhancers are further… (More)
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Highly Cited
2012
Highly Cited
2012
Pancreatic cancer is a highly lethal malignancy with few effective therapies. We performed exome sequencing and copy number… (More)
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Highly Cited
2012
Highly Cited
2012
Intellectual disability (ID) disorders are genetically and phenotypically highly heterogeneous and present a major challenge in… (More)
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2011
Highly Cited
2011
Structural rearrangements form a major class of somatic variation in cancer genomes. Local chromosome shattering, termed… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Colon cancer (CRC) development often includes chromosomal instability (CIN) leading to amplifications and deletions of… (More)
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Highly Cited
2006
Highly Cited
2006
Activating signal cointegrator-2 (ASC-2), a coactivator of multiple transcription factors that include retinoic acid receptor… (More)
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