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Lnc2Cancer: a manually curated database of experimentally supported lncRNAs associated with various human cancers
TLDR
The Lnc2Cancer database, which contains 1057 manually curated associations between 531 lncRNAs and 86 human cancers, will significantly improve the understanding of lncRNA deregulation in cancer and has the potential to be a timely and valuable resource. Expand
CellMarker: a manually curated resource of cell markers in human and mouse
TLDR
The CellMarker database is developed, aiming to provide a comprehensive and accurate resource of cell markers for various cell types in tissues of human and mouse, and a summarized marker prevalence in each cell type is graphically and intuitively presented through a vivid statistical graph. Expand
SubpathwayMiner: a software package for flexible identification of pathways
TLDR
An R-based software package (SubpathwayMiner) for flexible pathway identification and provides more flexibility in annotating gene sets and identifying the involved pathways (entire pathways and sub-pathways). Expand
SM2miR: a database of the experimentally validated small molecules' effects on microRNA expression
TLDR
The SM2miR database, which recorded 2925 relationships between 151 small molecules and 747 miRNAs in 17 species after manual curation from nearly 2000 articles, provides a fairly comprehensive repository about the influences of small molecules on miRNA expression, which will promote the development of miRNA therapeutics. Expand
Lnc2Cancer v2.0: updated database of experimentally supported long non-coding RNAs in human cancers
TLDR
The database has been updated with more data and several new features, and will be a useful resource platform for further understanding the associations between lncRNA and human cancer. Expand
QDMR: a quantitative method for identification of differentially methylated regions by entropy
TLDR
QDMR is presented, to quantify methylation difference and identify DMRs from genome-wide methylation profiles by adapting Shannon entropy, and provides an effective tool for the high-throughput identification of potential functional regions involved in epigenetic regulation. Expand
DiseaseEnhancer: a resource of human disease-associated enhancer catalog
TLDR
DiseaseEnhancer provides a promising avenue for researchers to facilitate the understanding of enhancer deregulation in disease pathogenesis, and identify new biomarkers for disease diagnosis and therapy. Expand
LincSNP 2.0: an updated database for linking disease-associated SNPs to human long non-coding RNAs and their TFBSs
TLDR
LincSNP 2.0 is a continually updated database that is used specifically to store and annotate disease-associated single nucleotide polymorphisms (SNPs) in human long non-coding RNAs (lncRNAs) and their transcription factor binding sites (TFBSs). Expand
In silico detection and characteristics of novel microRNA genes in the Equus caballus genome using an integrated ab initio and comparative genomic approach.
TLDR
This study will provide a reference point for further study on miRNAs identification in animals and improve the understanding of genome in horse. Expand
Walking the interactome to identify human miRNA-disease associations through the functional link between miRNA targets and disease genes
TLDR
A computational framework to identify miRNA-disease associations is developed, and a bipartite miRNAs-Disease network is constructed for systematically analyzing the global properties of miRNA regulation of disease genes. Expand
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