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KLRK1 gene

Known as: KLR, killer cell lectin like receptor K1, KLRK1 
This gene plays a role in the activation of natural killer cells.
National Institutes of Health

Related topics

Related topics

8 relations
KLRG1 geneLigand BindingNK Cell ActivationNKG2-D Type II Integral Membrane Protein

Narrower (2)

KLRK1 wt AlleleNK Cell Lectin-Like Receptor Subfamily K, Member 1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
NKG2D+ IFN-γ+ CD8+ T Cells Are Responsible for Palladium Allergy
Nickel, cobalt, and chromium are well known to be causal agents of allergic contact dermatitis. Palladium (Pd) can also cause… 
2014
2014
Polymorphisms in Genes Coding for the NK‐Cell Receptor NKG2D and its Ligand MICA in Recurrent Miscarriage
To investigate the possible association of Natural Killer Group (NKG) receptors gene polymorphisms and MHC class I chain‐related… 
Review
2012
Review
2012
Cancer immunotherapy using NKG2D and DNAM-1 systems.
Although tumor antigen-specific immunotherapy, such as dendritic cell vaccine, has recently emerged as a promising clinical… 
2012
2012
Ectopically-expressed human tumor biomarker MutS homologue 2 is a novel endogenous ligand that is recognized by human gammadelta T cells to induce innate anti-tumor/virus immunity
Background: Ectopically-expressed hMSH2 is tumor biomarker, however, the mechanism of its recognition is unclear. Results: hMSH2… 
2011
2011
Cutting Edge: NKG2D-Dependent Cytotoxicity Is Controlled by Ligand Distribution in the Target Cell Membrane
Although the importance of membrane microdomains in receptor-mediated activation of lymphocytes has been established, much less… 
2010
2010
Comparative genomic analysis of mammalian NKG2D ligand family genes provides insights into their origin and evolution
NKG2D is a major activating receptor of natural killer cells. Its ligands are major histocompatibility complex (MHC) class I-like… 
Highly Cited
2009
Highly Cited
2009
CD8dim and NKG2D Expression Defines Related Subsets of CD4+ T cells in HIV-Infected Patients With Worse Prognostic Factors
CD4+ T lymphocytes expressing CD8dim (DP: CD4+ CD8dim) or NKG2D represent cytotoxic effector populations, which have been… 
2008
2008
The expression and function of NKG2D molecule on intrahepatic CD8+ T cells in chronic viral hepatitis
Summary.  The natural killer (NK) cell receptor, NKG2D is a member of the c‐type lectin‐activating receptor family. It is… 
2002
2002
Cutting Edge: The Minor Histocompatibility Antigen H60 Peptide Interacts with Both H-2Kb and NKG2D1
Minor histocompatibility Ags elicit cell-mediated immune responses and graft rejection in individuals receiving MHC-matched… 
2001
2001
Molecular cloning and characterization of pig immunoreceptor DAP10 and NKG2D
Abstract. Pig immunoreceptor DAP10 cDNA was cloned from a peripheral blood lymphocyte (PBL) cDNA library using human DAP10 cDNA… 
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