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KLRG1 wt Allele

Known as: Mast Cell Function-Associated Antigen, Rat, Homolog of Gene, C-Type Lectin Domain Family 15, Member A Gene, MAFA-L 
Human KLRG1 wild-type allele is located in the vicinity of 12p13.31 and is approximately 108 kb in length. This allele, which encodes killer cell… Expand
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Type 2 diabetes (T2DM) commonly arises from islet β cell failure and insulin resistance. Here, we examined the sensitivity of key… Expand
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Highly Cited
2009
Highly Cited
2009
It has long been debated which aspects of music perception are universal and which are developed only after exposure to a… Expand
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Review
2006
Review
2006
The insulin gene is expressed almost exclusively in pancreatic beta-cells. Metabolic regulation of insulin gene expression… Expand
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Highly Cited
2005
Highly Cited
2005
ABSTRACT MafA is a transcription factor that binds to the promoter in the insulin gene and has been postulated to regulate… Expand
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Highly Cited
2005
Highly Cited
2005
Glucose toxicity in pancreatic islet beta cells causes loss of insulin gene expression, content, and secretion due to loss of… Expand
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Highly Cited
2005
Highly Cited
2005
The islet-enriched MafA, PDX-1, and BETA2 activators contribute to both β cell-specific and glucose-responsive insulin gene… Expand
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Highly Cited
2004
Highly Cited
2004
Insulin gene expression is regulated by several islet-enriched transcription factors. However, MafA is the only beta cell… Expand
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Highly Cited
2003
Highly Cited
2003
ABSTRACT The C1/RIPE3b1 (−118/−107 bp) binding factor regulates pancreatic-β-cell-specific and glucose-regulated transcription of… Expand
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Highly Cited
2002
Highly Cited
2002
The insulin gene is specifically expressed in β-cells of the Langerhans islets of the pancreas, and its transcription is… Expand
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Highly Cited
2002
Highly Cited
2002
Of the three critical enhancer elements that mediate β-cell-specific and glucose-responsive expression of the insulin gene, only… Expand
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