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KLRC1 wt Allele

Known as: Killer Cell Lectin-Like Receptor, Subfamily C, Member 1 Gene, NKG2, Killer Cell Lectin-Like Receptor Subfamily C, Member 1 wt Allele 
Human KLRC1 wild-type allele is located in the vicinity of 12p13 and is approximately 12 kb in length. This allele, which encodes NKG2-A/NKG2-B type… 
National Institutes of Health

Related topics

Related topics

7 relations
12p13Immune responseKLRC3 geneLigand Binding

Broader (1)

KLRC1 gene

Papers overview

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2011
2011
Development of Murine Hepatic NK Cells during Ontogeny: Comparison with Spleen NK Cells
The phenotype of developing liver NK cells (CD3−NK1.1+) was investigated during mouse ontogeny comparing with spleen NK cells… 
2010
2010
Assay of T- and NK-cell subsets and the expression of NKG2A and NKG2D in patients with new-onset systemic lupus erythematosus
This study aims to explore the percentage of T-cell and NK-cell subsets, the expression of NKG2A and NKG2D on CD3+ T cells and… 
Highly Cited
2005
Highly Cited
2005
Multiple Cytokines Regulate the NK Gene Complex-Encoded Receptor Repertoire of Mature NK Cells and T Cells1
Mature NK cells comprise a highly diverse population of lymphocytes that express different permutations of receptors to… 
2005
2005
Opposing effect of IFNgamma and IFNalpha on expression of NKG2 receptors: negative regulation of IFNgamma on NK cells.
The effector functions of natural killer (NK) cells are regulated by integrated signals across an array of stimulatory and… 
Highly Cited
2002
Highly Cited
2002
NK Cell Receptors of the Orangutan (Pongo pygmaeus): A Pivotal Species for Tracking the Coevolution of Killer Cell Ig-Like Receptors with MHC-C1
CD94, NKG2, Ly49, and killer cell Ig-like receptor (KIR) expressed by orangutan peripheral blood cells were examined by cloning… 
2002
2002
Cutting Edge: CD94/NKG2 Is Expressed on Th1 But Not Th2 Cells and Costimulates Th1 Effector Functions1
Th1 and Th2 cells can be phenotypically distinguished by very few cell surface markers. To identify cell surface molecules that… 
2002
2002
NK cells developing in vitro from fetal mouse progenitors express at least one member of the Ly49 family that is acquired in a time‐dependent and stochastic manner independently of CD94 and NKG2
NK cells developing in vitro from fetal progenitors in the presence of IL‐2 are phenotypically and functionally indistinguishable… 
2002
2002
Functional modulation of expanded CD8+ synovial fluid T cells by NK cell receptor expression in HLA-B27-associated reactive arthritis.
The aim of this study was to determine whether NK cell receptor (NKR) expression could modulate cytotoxicity of oligoclonal CD8… 
Review
1999
Review
1999
Why So Many Coinhibitory Receptors?
Receptors that display negative signalling functions on lymphocytes and other cells of the reticuloendothelial system now number… 
1997
1997
The human natural killer gene complex (NKC) is located on chromosome 12p13.1-p13.2
Induction of natural killer (NK) cell cytotoxicity is thought to be controlled by a balance between activating and inhibitory… 
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