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KLRB1 gene

Known as: hNKR-P1A, KLRB1, Killer Cell Lectin-Like Receptor Subfamily B, Member 1 Gene 
This gene plays a role in cytotoxicity and immune stimulation.
National Institutes of Health

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KLRB1 protein, humanLigand BindingNK Cell ActivationReceptor Signaling

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KLRB1 wt Allele

Papers overview

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2020
2020
Transcription/Expression of KLRB1 Gene as A Prognostic Indicator in Human Esophageal Squamous Cell Carcinoma.
AIM AND OBJECTIVE Esophageal squamous cell carcinoma (ESCC) is a cancer with worldwide distribution and dismal prognosis despite… 
2016
2016
Enhanced Th1/Th17 Functions of CD161+ CD8+ T Cells in Mucosal Tissues of Rhesus Macaques
Expression of the C-type lectin-like receptor CD161 by human T cells is associated with type-17 responses, which play critical… 
2016
2016
Influence of In Vitro IL-2 or IL-15 Alone or in Combination with Hsp 70 Derived 14-Mer Peptide (TKD) on the Expression of NK Cell Activatory and Inhibitory Receptors on Peripheral Blood T Cells, B…
Previous studies from Multhoff and colleagues reported that plasma membrane Hsp70 acts as a tumour-specific recognition structure… 
2016
2016
Gene expression profiles of putative biomarker candidates in Mycobacterium avium subsp. paratuberculosis-infected cattle.
This study was conducted to analyze the gene expression of prognostic potential biomarker candidates using the whole blood of… 
2011
2011
Structural analysis of natural killer cell receptor protein 1 (NKR-P1) extracellular domains suggests a conserved long loop region involved in ligand specificity
Receptor proteins at the cell surface regulate the ability of natural killer cells to recognize and kill a variety of aberrant… 
2003
2003
Expression cloning and function of the rat NK activating and inhibitory receptors NKR-P1A and -P1B.
We have characterized the rat NK receptors NKR-P1A and -P1B. A cDNA library was constructed from the rat NK cell line, RNK-16… 
2001
2001
Characterization of four new monoclonal antibodies that recognize mouse natural killer activation receptors.
With the aim of identifying natural killer (NK) activation receptors, we immunized BALB/c mice with (BALB/cxB6)F1 NK LAK cells… 
1998
1998
Phenotype of Rat Monocytes During Acute Kidney Allograft Rejection: Increased Expression of NKR‐P1 and Reduction of CD43
Monocytes and macrophages mediate cytotoxicity after appropriate activation and thus represent effectors secondary to T… 
1994
1994
Characterization and function of the NKR-P1dim/T cell receptor-alpha beta+ subset of rat T cells.
MHC-unrestricted cytotoxicity is mediated primarily by NK cells. However, some subsets of TCR-alpha beta+ and TCR-gamma delta+ T… 
1992
1992
Functional heterogeneity between NKR-P1bright/Lycopersicon esculentum lectin (L.E.)bright and NKR-P1bright/L.E.dim subpopulations of rat natural killer cells.
In this report, we present data on heterogeneity of rat NK cells utilizing a combination of antibody and lectin-binding… 
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