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KIR2DS4 wt Allele

Known as: KIR412, KIR2DS1, KIR1D 
Human KIR2DS4 wild-type allele is located in the vicinity of 19q13.4 and is approximately 16 kb in length. This allele, which encodes killer cell… Expand
National Institutes of Health

Related topics

Related topics

4 relations
19q13.4Immune responseLigand BindingReceptor Signaling

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
Haploidentical hematopoietic transplantation from KIR ligand-mismatched donors with activating KIRs reduces nonrelapse mortality.
Because activating killer cell immunoglobulinlike receptors (KIRs) are heterogeneously expressed in the population, we… Expand
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Highly Cited
2012
Highly Cited
2012
HLA-C-dependent prevention of leukemia relapse by donor activating KIR2DS1.
BACKGROUND Of the cancers treated with allogeneic hematopoietic stem-cell transplantation (HSCT), acute myeloid leukemia (AML) is… Expand
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Highly Cited
2007
Highly Cited
2007
KIRs and autoimmune disease: studies in systemic lupus erythematosus and scleroderma.
We investigated killer immunoglobulin-like receptors (KIRs) and the human leukocyte antigen (HLA)-C ligands for the corresponding… Expand
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2007
2007
Associations of killer cell immunoglobulin-like receptor genes with complications of rheumatoid arthritis
We investigated whether killer cell immunoglobulin-like receptor (KIR) genes are risk factor(s) for rheumatoid arthritis (RA) and… Expand
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2007
2007
Increased activating killer immunoglobulin-like receptor genes and decreased specific HLA-C alleles in couples with recurrent spontaneous abortion.
Accumulating evidence indicates natural killer (NK) cells play crucial roles in successful pregnancy. To investigate whether the… Expand
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Highly Cited
2004
Highly Cited
2004
Gene for the activating natural killer cell receptor, KIR2DS1, is associated with susceptibility to psoriasis vulgaris.
Psoriasis vulgaris, particularly its juvenile form, is strongly associated with the HLA-Cw*06 allele encoding the HLA-Cw6… Expand
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Highly Cited
2004
Highly Cited
2004
Genetic polymorphisms of killer cell immunoglobulin-like receptors are associated with susceptibility to psoriasis vulgaris.
To elucidate the association between killer cell immunoglobulin-like receptors (KIRs) and psoriasis vulgaris (PV), we typed 14… Expand
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Highly Cited
2002
Highly Cited
2002
Killer Ig-like receptor haplotype analysis by gene content: evidence for genomic diversity with a minimum of six basic framework haplotypes, each with multiple subsets.
Killer Ig-like receptor (KIR) genes constitute a multigene family whose genomic diversity is achieved through differences in gene… Expand
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Highly Cited
2002
Highly Cited
2002
A common KIR2DS4 deletion variant in the human that predicts a soluble KIR molecule analogous to the KIR1D molecule observed in the rhesus monkey.
A KIR2DS4 deletion variant allele, previously identified through KIR PCR-SSOP typing studies, was characterized, alongside a… Expand
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Highly Cited
2001
Highly Cited
2001
Diversity of the killer cell Ig-like receptors of rhesus monkeys.
Because the killer cell Ig-like receptors (KIRs) have only been characterized in humans and chimpanzees, we do not have a full… Expand
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