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KDR wt Allele

Known as: VEGFR, CD309, FLK1 
Human KDR wild-type allele is located within 4q11-q12 and is approximately 47 kb in length. This allele, which encodes vascular endothelial growth… 
National Institutes of Health

Related topics

Related topics

16 relations
4q11-q12Angiogenesis PathwayAngiogenic ProcessFocal adhesion pathway

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Dynasore impairs VEGFR2 signalling in an endocytosis-independent manner
VEGFR2 is a critical angiogenic receptor playing a key role in vascular homeostasis. Upon activation by VEGF, VEGFR2 becomes… 
2016
2016
Profiling of Vascular Endothelial Growth Factor Receptor Heterogeneity Identifies Protein Expression-defined Subclasses of Human Non-small Cell Lung Carcinoma.
BACKGROUND the vascular endothelial growth factor (VEGF) pathway plays a prominent role in the growth and progression of human… 
2014
2014
Increased VEGFR2 and MMP9 protein levels are associated with epithelial dysplasia grading.
2013
2013
Etv2 rescues Flk1 mutant embryoid bodies
Independent mouse knockouts of Etv2 and Flk1 are embryonic lethal and lack hematopoietic and endothelial lineages. We previously… 
2013
2013
Molecular analysis of a recurrent glioblastoma treated with bevacizumab
We treated a case of recurrent glioblastoma (GBM) with bevacizumab and assessed its effect biologically. A 55-year-old man with a… 
2012
2012
Single nucleotide polymorphism and serum levels of VEGFR2 are associated with age related macular degeneration.
Age-related macular degeneration (AMD) is a leading cause of blindness and is the third leading cause of blindness. Genetic… 
2009
2009
Molecular Targeted Enhanced Ultrasound Imaging of Flk1 Reveals Diagnosis and Prognosis Potential in a Genetically Engineered Mouse Prostate Cancer Model
Molecular imaging techniques used to detect the initiation of disease have the potential to provide the best opportunity for… 
2009
2009
Minimally invasive colon resection is associated with a transient increase in plasma sVEGFR1 levels and a decrease in sVEGFR2 levels during the early postoperative period
IntroductionPlasma vascular endothelial growth factor (VEGF) levels are elevated for 2–4 weeks after minimally invasive… 
2002
2002
Adenovirus-mediated delivery of a soluble form of the VEGF receptor Flk1 delays the growth of murine and human pancreatic adenocarcinoma in mice.
BACKGROUND Because pancreatic adenocarcinoma is poorly responsive to chemotherapy and radiation therapy, novel treatments such as… 
1998
1998
Direct visualization of renal vascular morphogenesis in Flk1 heterozygous mutant mice.
Flk1, a receptor tyrosine kinase for vascular endothelial growth factor (VEGF), is the earliest known marker for endothelial… 
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