KDR wt Allele

Known as: VEGFR, CD309, FLK1 
Human KDR wild-type allele is located within 4q11-q12 and is approximately 47 kb in length. This allele, which encodes vascular endothelial growth… (More)
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Flk1 is the major receptor for VEGF on endothelial cells. During embryogenesis, flk1 is required for both vasculogenesis and… (More)
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Highly Cited
2006
Highly Cited
2006
Receptor tyrosine kinase aberrations are implicated in the genesis of gliomas. We investigated expression and amplification of… (More)
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Highly Cited
2006
Highly Cited
2006
Endothelial cells respond to vascular endothelial growth factor (VEGF) to produce new blood vessels. This process of angiogenesis… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Fibrosis is the common end stage of most liver diseases, for which, unfortunately, there is no effective treatment… (More)
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Highly Cited
2004
Highly Cited
2004
The receptor tyrosine kinase FLK1 and the transcription factor SCL play crucial roles in the establishment of hematopoietic and… (More)
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Highly Cited
2003
Highly Cited
2003
Therapeutic angiogenesis is likely to require the administration of factors that complement each other. Activation of the… (More)
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Highly Cited
2003
Highly Cited
2003
Mouse embryos mutant for the VEGF receptor, VEGFR2, Flk-1, or Kdr, fail to form both endothelial and hematopoietic cells… (More)
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1998
1998
Flk1, a receptor tyrosine kinase for vascular endothelial growth factor (VEGF), is the earliest known marker for endothelial… (More)
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Highly Cited
1997
Highly Cited
1997
Mouse embryos lacking the receptor tyrosine kinase, Flk1, die without mature endothelial and hematopoietic cells. To investigate… (More)
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Highly Cited
1996
Highly Cited
1996
The tyrosine kinases Flt4, Flt1, and Flk1 (or KDR) constitute a family of endothelial cell-specific receptors with seven… (More)
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