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KAT2B gene

Known as: p300/CBP-ASSOCIATED FACTOR, GCN5, CAF 
This gene is involved in histone and nucleosome remodeling and transcriptional regulation.
National Institutes of Health

Related topics

Related topics

4 relations
Histone Acetyltransferase KAT2B, humanTranscriptional Regulationp300/CBP-Associated Factor

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KAT2B wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Gcn5 determines the fate of Drosophila germline stem cells through degradation of Cyclin A
The fluctuating CDK‐CYCLIN complex plays a general role in cell‐cycle control. Many types of stem cells use unique features of… 
2017
2017
Differential Effects of Histone Acetyltransferase GCN5 or PCAF Knockdown on Urothelial Carcinoma Cells
Disturbances in histone acetyltransferases (HATs) are common in cancers. In urothelial carcinoma (UC), p300 and CBP are often… 
2015
2015
Immunology: T-cell exhaustion limits immune reactivity and is associated with good prognosis in autoimmune disease
Immunology: T-cell exhaustion limits immune reactivity and is associated with good prognosis in autoimmune disease 
2010
2010
Genome-wide characterisation of the Gcn5 histone acetyltransferase in budding yeast during stress adaptation reveals evolutionarily conserved and diverged roles
BackgroundGcn5 is a transcriptional coactivator with histone acetyltransferase activity that is conserved with regard to… 
2008
2008
The STAGA Subunit ADA 2 b Is an Important Regulator of Human GCN 5 Catalysis †
Highly Cited
2005
Highly Cited
2005
GCN5: a supervisor in all-inclusive control of vertebrate cell cycle progression through transcription regulation of various cell cycle-related genes.
2005
2005
Histone H3 Ser10 Phosphorylation-Independent Function of Snf1 and Reg1 Proteins Rescues a gcn5− Mutant in HIS3 Expression
ABSTRACT Gcn5 protein is a prototypical histone acetyltransferase that controls transcription of multiple yeast genes. To… 
2001
2001
Mutational Analysis of Conserved Residues in the GCN5 Family of Histone Acetyltransferases*
GCN5 is a critical transcriptional co-activator and is the defining member of a large superfamily ofN-acetyltransferases. GCN5… 
1997
1997
Human histone acetyltransferase GCN5 exists in a stable macromolecular complex lacking the adapter ADA2.
Acetylation of core histones is an important regulatory step in transcriptional activation from chromatin templates. The yeast… 
1997
1997
ADA 1 , a Novel Component of the ADA / GCN 5 Complex , Has Broader Effects than GCN 5 , ADA 2 , or ADA 3
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