Histone Acetyltransferase KAT2B, human

Known as: p300/CBP-Associated Factor, Histone Acetylase PCAF, P/CAF 
Histone acetyltransferase KAT2B (832 aa, ~93 kDa) is encoded by the human KAT2B gene. This protein is involved in both histone acetylation and… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
To survive in hypoxic environments, organisms must be able to cope with redox imbalance and oxygen deficiency. The SIRT1… (More)
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Highly Cited
2004
Highly Cited
2004
Histone acetylation is a diagnostic feature of transcriptionally active genes. The proper recruitment and function of histone… (More)
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Highly Cited
2004
Highly Cited
2004
Apoptosis is a key tumor suppression mechanism that can be initiated by activation of the proapoptotic factor Bax. The Ku70 DNA… (More)
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Highly Cited
2002
Highly Cited
2002
Ligand activation of Notch receptors leads to release of the intracellular receptor domain (Notch IC), which translocates to the… (More)
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Highly Cited
2001
Highly Cited
2001
Acetylation of histones by p300/CBP and PCAF is considered to be a critical step in transcriptional regulation. In order to… (More)
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Highly Cited
2001
Highly Cited
2001
YY1 is a sequence-specific DNA-binding transcription factor that has many important biological roles. It activates or represses… (More)
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Highly Cited
1999
Highly Cited
1999
A number of transcriptional coactivators possess intrinsic histone acetylase activity, providing a direct link between… (More)
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Highly Cited
1999
Highly Cited
1999
The p53 tumor suppressor protein is a sequence-specific transcription factor that modulates the response of cells to DNA damage… (More)
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Highly Cited
1998
Highly Cited
1998
PCAF histone acetylase plays a role in regulation of transcription, cell cycle progression, and differentiation. Here, we show… (More)
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Highly Cited
1998
Highly Cited
1998
Whereas the histone acetylase PCAF has been suggested to be part of a coactivator complex mediating transcriptional activation by… (More)
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