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KAF156

 
National Institutes of Health

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Review
2018
Review
2018
INTRODUCTION Ganaplacide (previously known as KAF156) is a novel antimalarial compound part of the imidazolopiperazine family… Expand
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2017
2017
BackgroundKAF156 is a novel imidazolopiperazine anti-malarial with activity against pre-erythrocytic liver stages, asexual and… Expand
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2016
2016
BACKGROUND KAF156 belongs to a new class of antimalarial agents (imidazolopiperazines), with activity against asexual and sexual… Expand
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2016
2016
A molecular understanding of drug resistance mechanisms enables surveillance of the effectiveness of new antimicrobial therapies… Expand
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2016
2016
MMV007564 is a novel antimalarial benzimidazolyl piperidine chemotype identified in cellular screens. To identify the genetic… Expand
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2016
2016
Identification of polar metabolites of drug candidates during development is often challenging. Several prominent polar… Expand
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2015
2015
I diseases remain a significant cause of morbidity and mortality, among which tuberculosis (TB) and malaria are among the biggest… Expand
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2014
2014
Renewed global efforts toward malaria eradication have highlighted the need for novel antimalarial agents with activity against… Expand
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2014
2014
KAF156 belongs to a new class of antimalarial, the imidazolopiperazines, and is currently in clinical development for the… Expand
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2014
2014
Antimicrob. Agents Chemother.€2014, 58(9):5060. DOI:Thierry T. DiaganaSauerwein, Elizabeth A. Winzeler, Richard J. Glynne and… Expand
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