KAF156

 

Topic mentions per year

Topic mentions per year

2014-2016
02420142016

Papers overview

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2017
2017
KAF156 is a novel imidazolopiperazine anti-malarial with activity against pre-erythrocytic liver stages, asexual and sexual blood… (More)
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2016
2016
BACKGROUND KAF156 belongs to a new class of antimalarial agents (imidazolopiperazines), with activity against asexual and sexual… (More)
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2016
2016
MMV007564 is a novel antimalarial benzimidazolyl piperidine chemotype identified in cellular screens. To identify the genetic… (More)
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2016
2016
Identification of polar metabolites of drug candidates during development is often challenging. Several prominent polar… (More)
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2016
2016
A molecular understanding of drug resistance mechanisms enables surveillance of the effectiveness of new antimicrobial therapies… (More)
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Review
2016
Review
2016
Malaria is a major cause of morbidity and mortality in many African countries and parts of Asia and South America. Novel… (More)
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Review
2015
Review
2015
The burden of malaria has been considerably reduced over recent years. However, to achieve disease elimination, drug discovery… (More)
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Review
2015
Review
2015
INTRODUCTION Malaria is a major health problem in endemic countries and chemotherapy remains the most important tool in combating… (More)
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2014
2014
Renewed global efforts toward malaria eradication have highlighted the need for novel antimalarial agents with activity against… (More)
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2014
2014
KAF156 belongs to a new class of antimalarial, the imidazolopiperazines, and is currently in clinical development for the… (More)
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