KAF156
National Institutes of Health
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KAF156 is a novel imidazolopiperazine anti-malarial with activity against pre-erythrocytic liver stages, asexual and sexual blood…
ABSTRACT Introduction: Ganaplacide (previously known as KAF156) is a novel antimalarial compound part of the imidazolopiperazine…
Malaria remains a significant contributor to global human mortality, and roughly half the world’s population is at risk for…
BACKGROUND
KAF156 belongs to a new class of antimalarial agents (imidazolopiperazines), with activity against asexual and sexual…
A molecular understanding of drug resistance mechanisms enables surveillance of the effectiveness of new antimicrobial therapies…
MMV007564 is a novel antimalarial benzimidazolyl piperidine chemotype identified in cellular screens. To identify the genetic…
I diseases remain a significant cause of morbidity and mortality, among which tuberculosis (TB) and malaria are among the biggest…
ABSTRACT Renewed global efforts toward malaria eradication have highlighted the need for novel antimalarial agents with activity…
ABSTRACT KAF156 belongs to a new class of antimalarial, the imidazolopiperazines, and is currently in clinical development for…