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PurposeVasodilators are considered effective in the treatment of pulmonary hypertension if the vascular reactivity remains… Expand OBJECTIVES
We examined whether the adenosine triphosphate (ATP)-sensitive potassium (K(ATP)) channel openers (KCOs) block… Expand AIM
To study the influence of a novel KATP channel opener JTV-506(JTV) on cardiac function and myocardial infarct size of… Expand We compared the coronary and systemic hemodynamic effects of JTV-506, a novel potassium channel opener, with those of cromakalim… Expand The vascular effects of JTV-506 ((-)-(3S,4R)-2.2-bis(methoxymethyl)- 4-[(1,6-dihydro-l-methyl-6-oxo-3-pyridazinyl)amino]-3… Expand Effects of an ATP-sensitive K+ channel activator, JTV-506, on dual asthmatic responses and airway inflammation after antigen… Expand The antianginal effects of JTV-506, a newly synthesized 2,2-bis-methoxymethyl benzopyran-derivative potassium channel opener… Expand Background ATP‐sensitive K+ (KATP) channel activators produce relaxation of smooth muscle in many tissues. However, this wide… Expand Coronary vasodilator and hemodynamic profiles of JTV-506, a newly synthesized 2,2-bis-methoxymethyl benzopyran-derivative… Expand A variety of compounds having a benzopyran such as levcromakalim generally exhibit potent antihypertensive activity. During… Expand