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JTT 705

Known as: JTT-705, JTT705 
National Institutes of Health

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1 relation

Broader (1)

dalcetrapib

Papers overview

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Highly Cited
2009
Highly Cited
2009
Drug Discovery Using Chemical Systems Biology: Identification of the Protein-Ligand Binding Network To Explain the Side Effects of CETP Inhibitors
Systematic identification of protein-drug interaction networks is crucial to correlate complex modes of drug action to clinical… 
2009
2009
Cholesterylestertransfer protein inhibition and endothelial function in type II hyperlipidemia.
Review
2008
Review
2008
Targeting residual cardiovascular risk: raising high-density lipoprotein cholesterol levels
The last 20 years have witnessed dramatic reductions in cardiovascular risk using 3-hydroxy-3-methylglutaryl coenzyme A reductase… 
2007
2007
Cholesteryl ester transfer protein promotes the formation of cholesterol-rich remnant like lipoprotein particles in human plasma.
Review
2006
Review
2006
Therapeutic elevation of HDL-cholesterol to prevent atherosclerosis and coronary heart disease.
  • M. Chapman
  • Pharmacology and Therapeutics
  • 2006
  • Corpus ID: 23332566
Highly Cited
2005
Highly Cited
2005
Effectiveness of inhibition of cholesteryl ester transfer protein by JTT-705 in combination with pravastatin in type II dyslipidemia.
2004
2004
Inhibition of cholesteryl ester transfer protein increases serum apolipoprotein (apo) A-I levels by increasing the synthesis of apo A-I in rabbits.
Review
2004
Review
2004
Role of CETP inhibitors in the treatment of dyslipidemia
Purpose of review This review summarizes novel human data on cholesteryl ester-transfer protein (CETP) and atherosclerosis and… 
Highly Cited
2002
Highly Cited
2002
Cholesteryl ester transfer protein inhibitor (JTT-705) and the development of atherosclerosis in rabbits with severe hypercholesterolaemia.
Cholesteryl ester transfer protein (CETP) is a major determinant of plasma levels of high-density lipoprotein-cholesterol (HDL-C… 
Highly Cited
2000
Highly Cited
2000
bis(2-(Acylamino)phenyl) disulfides, 2-(acylamino)benzenethiols, and S-(2-(acylamino)phenyl) alkanethioates as novel inhibitors of cholesteryl ester transfer protein.
A series of bis(2-(acylamino)phenyl) disulfides, 2-(acylamino)benzenethiols, S-(2-(acylamino)phenyl) alkanethioates, and related… 
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