dalcetrapib

Known as: S-(2-((1-(2-ethylbutyl)cyclohexane)carbonylamino)phenyl) 2-methylpropanethioate 
A cholesteryl ester transfer protein (CETP) inhibitor that can produce an increase in serum HDL-cholesterol levels and a decrease in serum LDL… (More)
National Institutes of Health

Papers overview

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2015
2015
BACKGROUND Dalcetrapib did not improve clinical outcomes, despite increasing high-density lipoprotein cholesterol by 30%. These… (More)
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Highly Cited
2012
Highly Cited
2012
BACKGROUND In observational analyses, higher levels of high-density lipoprotein (HDL) cholesterol have been associated with a… (More)
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Highly Cited
2012
Highly Cited
2012
AIMS High-density lipoprotein cholesterol (HDL-C) is inversely associated with cardiovascular (CV) events and thus an attractive… (More)
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2012
2012
INTRODUCTION Cholesteryl ester transfer protein (CETP) plays an important role in reverse cholesterol transport by transferring… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Dalcetrapib modulates cholesteryl ester transfer protein (CETP) activity to raise high-density lipoprotein cholesterol… (More)
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2010
2010
AIMS Co-primary objectives were to evaluate dalcetrapib (JTT-705/RO4607381), which targets cholesteryl ester transfer protein… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Despite contemporary therapies for acute coronary syndrome (ACS), morbidity and mortality remain high. Low levels of… (More)
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Highly Cited
2009
Highly Cited
2009
Efficacy and safety data for dalcetrapib (RO4607381/JTT-705) are presented, following a report of increased mortality and cardiac… (More)
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2009
2009
BACKGROUND AND PURPOSE The association between torcetrapib and its off-target effects on blood pressure suggested a possible… (More)
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