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J 508

Known as: J-508 
National Institutes of Health

Papers overview

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2014
2014
Essential difference between the pharmacological spectrum of (−)-deprenyl and rasagiline
Highly Cited
2005
Highly Cited
2005
The possible mechanisms of action of (-)deprenyl in Parkinson's disease
(-)Deprenyl, a selective inhibitor of MAO-B, was found to be 60 times less potent in inhibiting intestinal MAO in the rat than… 
Review
1994
Review
1994
Behaviour of (-)-deprenyl and its analogues.
A number of new deprenyl analogues were synthesized during the last decades and structure-activity relationship studies were… 
1990
1990
Chromatographic studies on the binding, action and metabolism of (-)-deprenyl.
1989
1989
Determination of the absolute concentrations of monoamine oxidase A and B in human tissues.
1986
1986
Determination of monoamine oxidase concentrations in rat liver by inhibitor binding.
1986
1986
The effect of repeated administration of (-) deprenyl on the phenylethylamine-induced stereotypy in rats.
Phenylethylamine (PEA) in a dose of 40 mg/kg induces a moderate and short-lasting stereotype behaviour. The intensity and… 
1982
1982
The aphrodisiac effect of low doses of (-) deprenyl in male rats.
The effects of single doses of (-)deprenyl, in comparison to J-508, U-1424, pargyline and clorgyline, on the sexual performance… 
Highly Cited
1979
Highly Cited
1979
Does the B form selective monoamine oxidase inhibitor lose selectivity by long term treatment?
1979
1979
The inhibition of rat brain monoamine oxidase-B by J-508 (N-methyl-N-propargyl-(1-indanyl)-ammonium hydrochloride), and its use for the titration of this enzyme form.
The interaction between rat brain monoamine oxidase-B and J-508, an analogue of L-deprenil, has been investigated. J-508 inhibits… 
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