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Isocitrates

Known as: Isocitrates [Chemical/Ingredient], isocitrate 
Derivatives of isocitric acid, a structural isomer of CITRIC ACID, including its salts and esters.
National Institutes of Health

Related topics

Related topics

11 relations

Narrower (4)

2-nitroisocitrateisocitrateisocitric acidthreo-alpha-methylisocitrate
In Bloodagonistsantagonists & inhibitorsaspects of radiation effects

Broader (1)

tricarboxylate

Papers overview

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Highly Cited
2018
Highly Cited
2018
cIMPACT-NOW update 3: recommended diagnostic criteria for “Diffuse astrocytic glioma, IDH-wildtype, with molecular features of glioblastoma, WHO grade IV”
Working Committee 1 concluded that histologic grade II and III IDH-wildtype diffuse astrocytic gliomas that contain high-level… 
Highly Cited
2011
Highly Cited
2011
Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia
Acetyl coenzyme A (AcCoA) is the central biosynthetic precursor for fatty-acid synthesis and protein acetylation. In the… 
Highly Cited
2010
Highly Cited
2010
Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations
Mutations in isocitrate dehydrogenase 1 and 2 (IDH1/2), are present in most gliomas and secondary glioblastomas, but are rare in… 
Highly Cited
2009
Highly Cited
2009
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
Mutations in the enzyme cytosolic isocitrate dehydrogenase 1 (IDH1) are a common feature of a major subset of primary human brain… 
Review
2009
Review
2009
Regulation of mitochondrial dehydrogenases by calcium ions.
  • R. Denton
  • Biochimica et Biophysica Acta
  • 2009
  • Corpus ID: 31173684
Highly Cited
2005
Highly Cited
2005
Mycobacterium tuberculosis isocitrate lyases 1 and 2 are jointly required for in vivo growth and virulence
Genes involved in fatty acid catabolism have undergone extensive duplication in the genus Mycobacterium, which includes the… 
Highly Cited
2001
Highly Cited
2001
PLANT MITOCHONDRIA AND OXIDATIVE STRESS: Electron Transport, NADPH Turnover, and Metabolism of Reactive Oxygen Species.
  • I. Møller
  • Annual Review of Plant Physiology and Plant…
  • 2001
  • Corpus ID: 21296527
The production of reactive oxygen species (ROS), such as O2- and H2O2, is an unavoidable consequence of aerobic metabolism. In… 
Highly Cited
2000
Highly Cited
2000
Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase
Mycobacterium tuberculosis claims more human lives each year than any other bacterial pathogen. Infection is maintained in spite… 
Review
1972
Review
1972
Myocardial utilization of carbohydrate and lipids.
Highly Cited
1970
Highly Cited
1970
The metabolism of rat brain mitochondria. Preparation and characterization.
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