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Isocitrates
Known as:
Isocitrates [Chemical/Ingredient]
, isocitrate
Derivatives of isocitric acid, a structural isomer of CITRIC ACID, including its salts and esters.
National Institutes of Health
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Related topics
Related topics
11 relations
Narrower (4)
2-nitroisocitrate
isocitrate
isocitric acid
threo-alpha-methylisocitrate
In Blood
agonists
antagonists & inhibitors
aspects of radiation effects
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Broader (1)
tricarboxylate
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
cIMPACT-NOW update 3: recommended diagnostic criteria for “Diffuse astrocytic glioma, IDH-wildtype, with molecular features of glioblastoma, WHO grade IV”
D. Brat
,
K. Aldape
,
+9 authors
M. Weller
Acta Neuropathologica
2018
Corpus ID: 52844941
Working Committee 1 concluded that histologic grade II and III IDH-wildtype diffuse astrocytic gliomas that contain high-level…
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Highly Cited
2011
Highly Cited
2011
Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia
C. Metallo
,
P. Gameiro
,
+11 authors
G. Stephanopoulos
Nature
2011
Corpus ID: 4351812
Acetyl coenzyme A (AcCoA) is the central biosynthetic precursor for fatty-acid synthesis and protein acetylation. In the…
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Highly Cited
2010
Highly Cited
2010
Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations
S. Gross
,
R. Cairns
,
+10 authors
T. Mak
Journal of Experimental Medicine
2010
Corpus ID: 388113
Mutations in isocitrate dehydrogenase 1 and 2 (IDH1/2), are present in most gliomas and secondary glioblastomas, but are rare in…
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Highly Cited
2009
Highly Cited
2009
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
L. Dang
,
D. White
,
+17 authors
S. Su
Nature
2009
Corpus ID: 4414182
Mutations in the enzyme cytosolic isocitrate dehydrogenase 1 (IDH1) are a common feature of a major subset of primary human brain…
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Review
2009
Review
2009
Regulation of mitochondrial dehydrogenases by calcium ions.
R. Denton
Biochimica et Biophysica Acta
2009
Corpus ID: 31173684
Highly Cited
2005
Highly Cited
2005
Mycobacterium tuberculosis isocitrate lyases 1 and 2 are jointly required for in vivo growth and virulence
E. Muñoz-Elías
,
J. Mckinney
Nature Network Boston
2005
Corpus ID: 9616978
Genes involved in fatty acid catabolism have undergone extensive duplication in the genus Mycobacterium, which includes the…
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Highly Cited
2001
Highly Cited
2001
PLANT MITOCHONDRIA AND OXIDATIVE STRESS: Electron Transport, NADPH Turnover, and Metabolism of Reactive Oxygen Species.
I. Møller
Annual Review of Plant Physiology and Plant…
2001
Corpus ID: 21296527
The production of reactive oxygen species (ROS), such as O2- and H2O2, is an unavoidable consequence of aerobic metabolism. In…
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Highly Cited
2000
Highly Cited
2000
Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase
J. Mckinney
,
K. H. Z. Bentrup
,
+7 authors
D. Russell
Nature
2000
Corpus ID: 4384211
Mycobacterium tuberculosis claims more human lives each year than any other bacterial pathogen. Infection is maintained in spite…
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Review
1972
Review
1972
Myocardial utilization of carbohydrate and lipids.
J. R. Neely
,
M. Rovetto
,
J. Oram
Progress in cardiovascular diseases
1972
Corpus ID: 35017723
Highly Cited
1970
Highly Cited
1970
The metabolism of rat brain mitochondria. Preparation and characterization.
J. Clark
,
W. Nicklas
Journal of Biological Chemistry
1970
Corpus ID: 2276626
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