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Isocitrates

Known as: Isocitrates [Chemical/Ingredient], isocitrate 
Derivatives of isocitric acid, a structural isomer of CITRIC ACID, including its salts and esters.
National Institutes of Health

Related topics

Related topics

11 relations

Narrower (4)

2-nitroisocitrateisocitrateisocitric acidthreo-alpha-methylisocitrate
In Bloodagonistsantagonists & inhibitorsaspects of radiation effects
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Broader (1)

tricarboxylate

Papers overview

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Review
2019
Review
2019
Epigenetic therapy combinations in acute myeloid leukemia: what are the options?
Epigenetics refers to the regulation of gene expression mainly by changes in DNA methylation and modifications of histone… Expand
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Review
2019
Review
2019
Micromanaging aerobic respiration and glycolysis in cancer cells
Background Cancer cells possess a common metabolic phenotype, rewiring their metabolic pathways from mitochondrial oxidative… Expand
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Review
2018
Review
2018
Temozolomide-associated hypermutation in gliomas.
Low-grade gliomas cause considerable morbidity and most will recur after initial therapy. At recurrence, low-grade gliomas can… Expand
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Review
2018
Review
2018
Glioma CpG island methylator phenotype (G-CIMP): biological and clinical implications.
Gliomas are a heterogeneous group of brain tumors with distinct biological and clinical properties. Despite advances in surgical… Expand
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Review
2018
Review
2018
Prediction of IDH1-Mutation and 1p/19q-Codeletion Status Using Preoperative MR Imaging Phenotypes in Lower Grade Gliomas
BACKGROUND AND PURPOSE: WHO grade II gliomas are divided into three classes: isocitrate dehydrogenase (IDH)-wildtype, IDH-mutant… Expand
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Review
2018
Review
2018
The T2-FLAIR mismatch sign as an imaging marker for non-enhancing IDH-mutant, 1p/19q-intact lower-grade glioma: a validation study
Background The purpose of this study was to assess the reproducibility of the previously described T2-fluid attenuated inversion… Expand
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Review
2017
Review
2017
Isocitrate dehydrogenases in physiology and cancer: biochemical and molecular insight
Isocitrate dehydrogenases play important roles in cellular metabolism and cancer. This review will discuss how the roles of… Expand
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Highly Cited
2009
Highly Cited
2009
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
Mutations in the enzyme cytosolic isocitrate dehydrogenase 1 (IDH1) are a common feature of a major subset of primary human brain… Expand
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Highly Cited
2005
Highly Cited
2005
Mycobacterium tuberculosis isocitrate lyases 1 and 2 are jointly required for in vivo growth and virulence
Genes involved in fatty acid catabolism have undergone extensive duplication in the genus Mycobacterium, which includes the… Expand
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Highly Cited
2000
Highly Cited
2000
Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase
Mycobacterium tuberculosis claims more human lives each year than any other bacterial pathogen. Infection is maintained in spite… Expand
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