isocitrate
National Institutes of Health
Papers overview
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Background: Mutations in IDH2 occur in 8-19% of patients (pts) with AML. Enasidenib (ENA; AG-221) is an oral, small-molecule…
Introduction : IDH2 mutations (m IDH2 ) are recurrent in ~5% of patients (pts) with MDS and ~15% of pts with acute myeloid…
Evidence suggests that specific mutations of isocitrate dehydrogenases 1 and 2 (IDH1/2) are critical for the initiation and…
Expression of many components of the secretory pathway in peptidergic neuroendocrine cells is precisely controlled in response to…