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Isocitrate Lyase

Known as: Isocitratase, Isocitrate Lyase [Chemical/Ingredient], Isocitrate glyoxylate-lyase 
A key enzyme in the glyoxylate cycle. It catalyzes the conversion of isocitrate to succinate and glyoxylate. EC 4.1.3.1.
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Immunoresponsive gene 1 (Irg1) is highly expressed in mammalian macrophages during inflammation, but its biological function has… Expand
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Highly Cited
2010
Highly Cited
2010
The ability of Mycobacterium tuberculosis to persist in its human host despite extensive chemotherapy is thought to be based on… Expand
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Review
2009
Review
2009
The glyoxylate cycle is an anaplerotic pathway of the tricarboxylic acid (TCA) cycle that allows growth on C(2) compounds by… Expand
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Highly Cited
2006
Highly Cited
2006
The role of isocitrate lyase (ICL) in the glyoxylate cycle and its necessity for persistence and virulence of Mycobacterium… Expand
Highly Cited
2005
Highly Cited
2005
Genes involved in fatty acid catabolism have undergone extensive duplication in the genus Mycobacterium, which includes the… Expand
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Highly Cited
2001
Highly Cited
2001
Candida albicans, a normal component of the mammalian gastrointestinal flora, is responsible for most fungal infections in… Expand
Highly Cited
2000
Highly Cited
2000
Mycobacterium tuberculosis claims more human lives each year than any other bacterial pathogen. Infection is maintained in spite… Expand
Highly Cited
2000
Highly Cited
2000
Isocitrate lyase (ICL) plays a pivotal role in the persistence of Mycobacterium tuberculosis in mice by sustaining intracellular… Expand
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Highly Cited
1977
Highly Cited
1977
Enzymes catalyzing steps from ethanol to acetyl-coenzyme A, from malate to pyruvate, and from pyruvate to glucose 6-phosphate… Expand
Highly Cited
1968
Highly Cited
1968
Acetate (1 to 10 mm) had no effect on the rate of nitrite oxidation or exponential growth by Nitrobacter agilis. However, acetate… Expand