Isocitrate Lyase

Known as: Isocitratase, Isocitrate Lyase [Chemical/Ingredient], Isocitrate glyoxylate-lyase 
A key enzyme in the glyoxylate cycle. It catalyzes the conversion of isocitrate to succinate and glyoxylate. EC 4.1.3.1.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1957-2018
0204019572017

Papers overview

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Highly Cited
2010
Highly Cited
2010
The ability of Mycobacterium tuberculosis to persist in its human host despite extensive chemotherapy is thought to be based on… (More)
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Highly Cited
2005
Highly Cited
2005
Genes involved in fatty acid catabolism have undergone extensive duplication in the genus Mycobacterium, which includes the… (More)
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Highly Cited
2002
Highly Cited
2002
A pathogenicity gene has been identified in Leptosphaeria maculans, the ascomycetous fungus that causes blackleg disease of… (More)
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Highly Cited
2001
Highly Cited
2001
Candida albicans, a normal component of the mammalian gastrointestinal flora, is responsible for most fungal infections in… (More)
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Highly Cited
2000
Highly Cited
2000
Mycobacterium tuberculosis claims more human lives each year than any other bacterial pathogen. Infection is maintained in spite… (More)
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Highly Cited
2000
Highly Cited
2000
Isocitrate lyase (ICL) plays a pivotal role in the persistence of Mycobacterium tuberculosis in mice by sustaining intracellular… (More)
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Highly Cited
1997
Highly Cited
1997
Isocitrate lyase (IL) is an essential enzyme in the glyoxylate cycle, which is a pathway involved in the mobilization of stored… (More)
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Highly Cited
1989
Highly Cited
1989
We have analyzed the temporal and spatial expression of genes encoding the glycoxylate cycle enzymes isocitrate lyase and malate… (More)
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1980
1980
Biosynthesis of isocitrate lyase, a tetrameric enzyme of the glyoxysomal matrix, was studied in Neurospora crassa, in which the… (More)
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1977
1977
Enzymes catalyzing steps from ethanol to acetyl-coenzyme A, from malate to pyruvate, and from pyruvate to glucose 6-phosphate… (More)
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