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Iodine I 123 Anti-CEA Recombinant Diabody T84.66
A radioimmunoconjugate comprised of a recombinant scFv dimer diabody of a monoclonal antibody against human carcinoembryonic antigen (CEA) labeled…
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National Institutes of Health
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Highly Cited
2015
Highly Cited
2015
Diabody Pretargeting with Click Chemistry In Vivo
Sander M. J. van Duijnhoven
,
R. Rossin
,
S. M. van den Bosch
,
M. Wheatcroft
,
P. Hudson
,
M. Robillard
Journal of Nuclear Medicine
2015
Corpus ID: 24074018
Radioimmunotherapy and nuclear imaging (immuno-PET/SPECT) of cancer with radiometal-labeled antibody fragments or peptides is…
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2010
2010
Evaluation of the Anti-HER2 C6.5 Diabody as a PET Radiotracer to Monitor HER2 status and Predict Response to Trastuzumab Treatment
S. Reddy
,
C. Shaller
,
+4 authors
M. Robinson
Clinical Cancer Research
2010
Corpus ID: 8960379
Purpose: The rapid tumor targeting and pharmacokinetic properties of engineered antibodies make them potentially suitable for use…
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Highly Cited
2009
Highly Cited
2009
Tumor Immunotherapy Using Gene-Modified Human Mesenchymal Stem Cells Loaded into Synthetic Extracellular Matrix Scaffolds
M. Compte
,
A. Cuesta
,
+4 authors
L. Álvarez-Vallina
Stem Cells
2009
Corpus ID: 690990
Mesenchymal stem cells (MSCs) are appealing as gene therapy cell vehicles given their ease of expansion and transduction. However…
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Highly Cited
2008
Highly Cited
2008
Anti-CD30 diabody-drug conjugates with potent antitumor activity
Kristine M Kim
,
C. McDonagh
,
+11 authors
P. Carter
Molecular Cancer Therapeutics
2008
Corpus ID: 39080824
Anti-CD30 diabodies were engineered with two cysteine mutations for site-specific drug conjugation in each chain of these…
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Highly Cited
2007
Highly Cited
2007
Fusion of Gaussia Luciferase to an Engineered Anti-carcinoembryonic Antigen (CEA) Antibody for In Vivo Optical Imaging
K. Venisnik
,
T. Olafsen
,
S. Gambhir
,
A. Wu
Molecular Imaging and Biology
2007
Corpus ID: 11127384
The bioluminescent protein Gaussia luciferase (GLuc) was fused to an anti-carcinoembryonic antigen (CEA) antibody fragment, the…
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Highly Cited
2006
Highly Cited
2006
Humanization of the Bispecific Epidermal Growth Factor Receptor × CD3 Diabody and Its Efficacy as a Potential Clinical Reagent
R. Asano
,
Y. Sone
,
+6 authors
I. Kumagai
Clinical Cancer Research
2006
Corpus ID: 14918115
Purpose: Bispecific antibodies (BsAb) have been exploited as both cancer immunodiagnostics and cancer therapeutics and show…
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Highly Cited
2006
Highly Cited
2006
Bifunctional antibody-Renilla luciferase fusion protein for in vivo optical detection of tumors.
K. Venisnik
,
T. Olafsen
,
A. Loening
,
M. Iyer
,
S. Gambhir
,
A. Wu
Protein engineering, design & selection : PEDS
2006
Corpus ID: 20672800
An anti-carcinoembryonic antigen (CEA) antibody fragment, the anti-CEA diabody, was fused to the bioluminescence enzyme Renilla…
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Highly Cited
2003
Highly Cited
2003
Effect of domain order on the activity of bacterially produced bispecific single-chain Fv antibodies.
S. Kipriyanov
,
G. Moldenhauer
,
+6 authors
M. Little
Journal of Molecular Biology
2003
Corpus ID: 39614163
2002
2002
A mutated superantigen SEA D227A fusion diabody specific to MUC1 and CD3 in targeted cancer immunotherapy for bile duct carcinoma
S. Takemura
,
T. Kudo
,
+11 authors
I. Kumagai
Cancer Immunology and Immunotherapy
2002
Corpus ID: 21976715
Abstract. In cancer immunotherapy research, many bispecific antibodies (BsAbs) have been developed for directing T cells toward…
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Highly Cited
1999
Highly Cited
1999
A bispecific diabody that mediates natural killer cell cytotoxicity against xenotransplantated human Hodgkin's tumors.
Michaela A. E. Arndt
,
Jürgen Krauss
,
Sergey Kipriyanov
,
Michael G. Pfreundschuh
,
Melvyn Little
Blood
1999
Corpus ID: 18175291
CD16/CD30 bispecific monoclonal antibodies can induce remissions of Hodgkin's disease refractory to chemo- and radiotherapy…
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