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Iodine I-123 ADAM

Known as: ADAM I-123, Iodine-123-labeled 2-((2-((dimethylamino)methyl)phenyl)thio)-5-iodophenylamine 
A radiopharmaceutical containing the serotonin transporter (SERT) ligand ADAM [2-((2-((dimethylamino)methyl)phenyl)thio)-5-iodophenylamine] labeled… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Serotonin transporter gene promoter polymorphisms modify the association between paroxetine serotonin transporter occupancy and clinical response in major depressive disorder
Background In major depressive disorder, selective serotonin reuptake inhibitors target the serotonin transporter (SERT). Their… Expand
Highly Cited
2004
Highly Cited
2004
Levodopa and the progression of Parkinson's disease.
BACKGROUND Despite the known benefit of levodopa in reducing the symptoms of Parkinson's disease, concern has been expressed that… Expand
Highly Cited
1998
Highly Cited
1998
Impaired regional fatty acid uptake and systolic dysfunction in hypertrophied right ventricle.
UNLABELLED Little information is available regarding the determinants of systolic contractile function of the hypertrophied right… Expand
Highly Cited
1997
Highly Cited
1997
Correlation between reduced in vivo benzodiazepine receptor binding and severity of psychotic symptoms in schizophrenia.
OBJECTIVE Although there is evidence from postmortem studies suggestive of deficient inhibitory neurotransmission of gamma… Expand
1997
1997
Assessment of benzodiazepine receptors using iodine-123-labeled iomazenil single-photon emission computed tomography in patients with ischemic cerebrovascular disease. A comparison with PET study.
BACKGROUND AND PURPOSE [123I]Iomazenil (IMZ) is a tracer used for single-photon emission computed tomography (SPECT) that has the… Expand
Highly Cited
1996
Highly Cited
1996
Iodine-123-IPT SPECT imaging of CNS dopamine transporters: nonlinear effects of normal aging on striatal uptake values.
UNLABELLED Iodine-123-labeled IPT (N-(3-iodopropen-2-yl)-2 beta-carbomethoxy-3 beta-(4-chlorophenyl)tropane) is an analog of… Expand
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Highly Cited
1994
Highly Cited
1994
Synthesis and characterization of radioiodinated N-(3-iodopropen-1-yl)-2 beta-carbomethoxy-3 beta-(4-chlorophenyl)tropanes: potential dopamine reuptake site imaging agents.
Methods have been developed for the preparation of radioiodinated N-substituted 2 beta-carbomethoxy-3 beta-(4-chlorophenyl… Expand
Highly Cited
1994
Highly Cited
1994
Compartmental modeling of iodine-123-iodobenzofuran binding to dopamine D2 receptors in healthy subjects.
UNLABELLED Iodine-123-labeled iodobenzofuran ([123I]IBF) is a potent dopamine D2 antagonist that provides good visualization of… Expand
Highly Cited
1986
Highly Cited
1986
Application of iodine-123-labeled isopropylamphetamine imaging to the study of dementia.
Forty-seven patients diagnosed as clinically demented were imaged with 123I isopropylamphetamine (IMP). All of these patients… Expand
1986
1986
Frequency and patterns of abnormality detected by iodine-123 amine emission CT after cerebral infarction.
Single photon emission computed tomography (SPECT) was performed in 31 patients with cerebral infarction and 13 who had had… Expand
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