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Interleukin-7

Known as: Interleukin 7 Precursor, Lymphopoietin-1, IL7 
One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. IL-7 is made by cells that cover and support… 
National Institutes of Health

Related topics

Related topics

28 relations
Cell Proliferation Regulatory ProcessCytokine GeneCytokine Receptor BindingCytokine Signaling

Broader (3)

Hematopoietic Cell Growth FactorsRecombinant Interleukin-7cytokine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
Interleukin-7 restores lymphocytes in septic shock: the IRIS-7 randomized clinical trial.
BACKGROUND A defining pathophysiologic feature of sepsis is profound apoptosis-induced death and depletion of CD4+ and CD8+ T… 
Highly Cited
2009
Highly Cited
2009
Interleukin 7 signaling in dendritic cells regulates the homeostatic proliferation and niche size of CD4+ T cells
Interleukin 7 (IL-7) and T cell antigen receptor signals have been proposed to be the main drivers of homeostatic T cell… 
Review
2007
Review
2007
Interleukin-7 receptor expression: intelligent design
Interleukin-7 (IL-7) is produced by stromal cells in lymphoid tissues and is required for the development of T cells and for… 
Highly Cited
2007
Highly Cited
2007
Risk alleles for multiple sclerosis identified by a genomewide study.
BACKGROUND Multiple sclerosis has a clinically significant heritable component. We conducted a genomewide association study to… 
Highly Cited
2005
Highly Cited
2005
Interleukin-7 is necessary to maintain the B cell potential in common lymphoid progenitors
Interleukin-7 (IL-7) promotes survival and expansion of lymphoid precursors. We show here that, in addition, IL-7 has a… 
Review
2005
Review
2005
Infections and autoimmune diseases.
Highly Cited
1997
Highly Cited
1997
Bcl-2 Rescues T Lymphopoiesis in Interleukin-7 Receptor–Deficient Mice
Highly Cited
1993
Highly Cited
1993
Cutaneous lymphoproliferation and lymphomas in interleukin 7 transgenic mice
To investigate the role of interleukin 7 (IL-7) in the development of the lymphoid system, we have generated two lines of… 
Highly Cited
1993
Highly Cited
1993
Inhibition of murine B and T lymphopoiesis in vivo by an anti- interleukin 7 monoclonal antibody
The effects of interleukin 7 (IL-7) on the growth and differentiation of murine B cell progenitors has been well characterized… 
Highly Cited
1988
Highly Cited
1988
Stimulation of B-cell progenitors by cloned murine interleukin-7
The events involved in the commitment and development of lymphoid lineage cells are poorly understood. We have used a recently… 
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