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Interleukin-7

Known as: Interleukin 7 Precursor, Lymphopoietin-1, IL7 
One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. IL-7 is made by cells that cover and support… 
National Institutes of Health

Related topics

Related topics

28 relations
Cell Proliferation Regulatory ProcessCytokine GeneCytokine Receptor BindingCytokine Signaling

Broader (3)

Hematopoietic Cell Growth FactorsRecombinant Interleukin-7cytokine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Blockade of the interleukin-7 receptor inhibits collagen-induced arthritis and is associated with reduction of T cell activity and proinflammatory mediators.
OBJECTIVE To study the effects of interleukin-7 receptor α-chain (IL-7Rα) blockade on collagen-induced arthritis (CIA) and to… 
Highly Cited
2005
Highly Cited
2005
Modulation of interleukin-7 receptor expression characterizes differentiation of CD8 T cells specific for HIV, EBV and CMV
Objectives:To further understand differentiation and homeostasis of CD8 T cells specific for HIV, Epstein–Barr Virus (EBV) and… 
Highly Cited
2002
Highly Cited
2002
Effects of exogenous interleukin-7 on human thymus function.
Immune reconstitution is a critical component of recovery after treatment of human immunodeficiency virus (HIV) infection, cancer… 
Review
2002
Review
2002
Cooperation between IL-7 and the pre-B cell receptor: a key to B cell selection.
Highly Cited
2001
Highly Cited
2001
Interleukin-7 in Plasma Correlates with CD4 T-Cell Depletion and May Be Associated with Emergence of Syncytium-Inducing Variants in Human Immunodeficiency Virus Type 1-Positive Individuals
ABSTRACT Human immunodeficiency virus type 1 (HIV-1) primary infection is characterized by the use of CCR5 as a coreceptor for… 
Highly Cited
1996
Highly Cited
1996
Interleukin-7 is a critical growth factor in early human T-cell development.
Highly purified human CD34+ fetal liver stem cells differentiate to mature T cells when seeded in vitro into isolated fetal… 
Highly Cited
1996
Highly Cited
1996
Combined signaling through interleukin-7 receptors and flt3 but not c-kit potently and selectively promotes B-cell commitment and differentiation from uncommitted murine bone marrow progenitor cells.
Multiple cytokines can synergize to stimulate the in vitro proliferation and exclusive myeloid differentiation of multipotent… 
Highly Cited
1992
Highly Cited
1992
Chromosomal localization and organization of the murine genes encoding the beta subunits (AIC2A and AIC2B) of the interleukin 3, granulocyte/macrophage colony-stimulating factor, and interleukin 5…
Highly Cited
1992
Highly Cited
1992
Administration of human recombinant IL-7 to normal and irradiated mice increases the numbers of lymphocytes and some immature cells of the myeloid lineage.
In vitro experiments performed by several investigators have demonstrated that IL-7 is a growth factor for immature B lymphocytes… 
Highly Cited
1991
Highly Cited
1991
Human interleukin-7 induces proliferation of neoplastic cells from chronic lymphocytic leukemia and acute leukemias.
The biologic effects of interleukin-7 (IL-7) and the expression of specific IL-7 membrane receptors on isolated neoplastic cells… 
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