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Interleukin-15 Receptor alpha Subunit

Known as: IL-15R alpha, Interleukin 15 Receptor alpha, Interleukin-15 Receptor alpha Subunit [Chemical/Ingredient] 
A low affinity interleukin-15 receptor subunit that combines with the INTERLEUKIN-2 RECEPTOR BETA SUBUNIT and the INTERLEUKIN RECEPTOR COMMON GAMMA… 
National Institutes of Health

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IL15RA geneIn Bloodagonistsantagonists & inhibitors

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Interleukin-15 Receptor Subunit Alpha, human

Papers overview

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Review
2010
Review
2010
Trans-presentation: a novel mechanism regulating IL-15 delivery and responses.
Highly Cited
2009
Highly Cited
2009
Macrophage- and dendritic-cell-derived interleukin-15 receptor alpha supports homeostasis of distinct CD8+ T cell subsets.
2009
2009
Human renal cancer cells express a novel membrane-bound interleukin-15 that induces, in response to the soluble interleukin-15 receptor alpha chain, epithelial-to-mesenchymal transition.
Although interleukin-15 (IL-15) is a powerful immunomodulatory factor that has been proposed for cancer immunotherapy, its… 
Highly Cited
2007
Highly Cited
2007
The SLAM-associated protein signaling pathway is required for development of CD4+ T cells selected by homotypic thymocyte interaction.
Review
2005
Review
2005
The roles of interleukin-15 receptor alpha: trans-presentation, receptor component, or both?
Interleukin-15 receptor alpha (IL-15R alpha) is a high affinity IL-15 binding protein that is crucial for mediating IL-15… 
Highly Cited
2004
Highly Cited
2004
Natural, Proteolytic Release of a Soluble Form of Human IL-15 Receptor α-Chain That Behaves as a Specific, High Affinity IL-15 Antagonist1
IL-15 and IL-2 are two structurally and functionally related cytokines whose high affinity receptors share the IL-2R β-chain and… 
Highly Cited
2004
Highly Cited
2004
Identification of an Interleukin-15α Receptor-binding Site on Human Interleukin-15*
To identify the epitopes in human interleukin-15 (IL-15) that are responsible for binding to the interleukin-15 receptor α chain… 
2003
2003
Mast Cells Express Novel Functional IL-15 Receptor α Isoforms1
Mast cells previously have been reported to be regulated by IL-15 and to express a distinct IL-15R, termed IL-15RX. To further… 
Highly Cited
1999
Highly Cited
1999
Natural Splicing of Exon 2 of Human Interleukin-15 Receptor α-Chain mRNA Results in a Shortened Form with a Distinct Pattern of Expression*
We report the existence of eight different interleukin-15 receptor α-chain (IL-15Rα) transcripts resulting from exon-splicing… 
Highly Cited
1995
Highly Cited
1995
Functional Characterization of the Human Interleukin-15 Receptor αChain and Close Linkage of IL15RA and IL2RA Genes (*)
Interleukins-2 and −15 (IL-2 and IL-15) are cytokines with overlapping but distinct biological effects. Their receptors share two… 
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