Interferon-Induced Helicase, IFIH1

Known as: Interferon-Induced Helicase C Domain-Containing Protein 1, Melanoma Differentiation-Associated Protein 5, CADM-140 Autoantigen 
A DEAD box RNA helicase that contains two N-terminal CASPASE ACTIVATION AND RECRUITMENT DOMAINS. It functions as a sensor of viral NUCLEIC ACIDS such… (More)
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Retinoic acid-inducible gene 1 (RIG-I) and melanoma differentiation-associated protein 5 (MDA5) are paralogous receptors for… (More)
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Highly Cited
2010
Highly Cited
2010
MCM2-7 proteins provide essential helicase functions in eukaryotes at chromosomal DNA replication forks. During the G1 phase of… (More)
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Highly Cited
2009
Highly Cited
2009
Genome-wide association studies (GWASs) are regularly used to map genomic regions contributing to common human diseases, but they… (More)
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Highly Cited
2009
Highly Cited
2009
OBJECTIVE To identify the autoantigen recognized by the autoantibody that is associated with clinically amyopathic… (More)
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Highly Cited
2009
Highly Cited
2009
The eukaryotic replisome is a crucial determinant of genome stability, but its structure is still poorly understood. We found… (More)
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Highly Cited
2008
Highly Cited
2008
Fanconi anemia (FA) is a heritable human cancer-susceptibility disorder, delineating a genetically heterogenous pathway for the… (More)
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Highly Cited
2007
Highly Cited
2007
The MCM2-7 helicase complex is loaded on DNA replication origins during the G1 phase of the cell cycle to license the origins for… (More)
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Highly Cited
2007
Highly Cited
2007
The complex between the DnaB helicase and the DnaG primase unwinds duplex DNA at the eubacterial replication fork and synthesizes… (More)
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Highly Cited
2005
Highly Cited
2005
In eukaryotes, numerous lines of evidence have coalesced into a convincing case that the MCM2-7 complex - a heterohexameric… (More)
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Highly Cited
1997
Highly Cited
1997
We report here that DNA double-strand breaks (DSBs) form in Escherichia coli upon arrest of replication forks due to a defect in… (More)
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