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IFIH1 protein, human

Known as: Interferon-Induced Helicase C Domain-Containing Protein 1, MDA-5 protein, human, Melanoma Differentiation-Associated Protein 5 
Interferon-induced helicase C domain-containing protein 1 (1025 aa, ~117 kDa) is encoded by the human IFIH1 gene. This protein is involved in the… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
The innate immune system senses nucleic acids by germline-encoded pattern recognition receptors. RNA is sensed by Toll-like… Expand
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Highly Cited
2009
Highly Cited
2009
The innate immune system senses RNA virus infections through membrane-bound Toll-like receptors or the cytoplasmic proteins RIG-I… Expand
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Highly Cited
2009
Highly Cited
2009
Modified vaccinia virus Ankara (MVA) is an attenuated double-stranded DNA poxvirus currently developed as a vaccine vector… Expand
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Highly Cited
2009
Highly Cited
2009
Untreated HIV-1 infection progresses through acute and asymptomatic stages to AIDS. Although each of the three stages has well… Expand
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Highly Cited
2008
Highly Cited
2008
Noroviruses are important human pathogens responsible for most cases of viral epidemic gastroenteritis worldwide. Murine… Expand
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Highly Cited
2008
Highly Cited
2008
BackgroundThe DExD/H domain containing RNA helicases such as retinoic acid-inducible gene I (RIG-I) and melanoma differentiation… Expand
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Highly Cited
2007
Highly Cited
2007
Influenza A virus (IAV) triggers a contagious acute respiratory disease that causes considerable mortality annually. Recently, we… Expand
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Highly Cited
2007
Highly Cited
2007
ABSTRACT Infections with RNA viruses are sensed by the innate immune system through membrane-bound Toll-like receptors or the… Expand
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Review
2006
Review
2006
Poliovirus was first isolated nearly 100 years ago in a landmark experiment that established the viral etiology of poliomyelitis… Expand
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Highly Cited
2002
Highly Cited
2002
Human melanoma cells can be reprogrammed to terminally differentiate and irreversibly lose proliferative capacity by appropriate… Expand
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