Interferon Alpha, Human

Known as: Interferon Alfa-N3, Human leukocyte interferon, alfa-n3 interferon 
A class of interferon (leukocyte interferon) produced predominantly by B lymphocytes. Located in a cluster on 9p22 there are at least 13 functional… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1977-2018
0102019772018

Papers overview

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2010
2010
Type I interferon (IFN) inhibits virus replication by activating multiple antiviral mechanisms and pathways. It has long been… (More)
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2009
2009
Chronic immune activation is a driver of human immunodeficiency virus type 1 (HIV-1) disease progression. Here, we describe that… (More)
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2006
2006
Host factors involved in viral replication are potentially attractive antiviral targets that are complementary to specific… (More)
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2004
2004
Human T-cell lymphotropic virus type 1 associated adult T-cell leukemia/lymphoma carries a very poor prognosis due to its… (More)
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Highly Cited
2000
Highly Cited
2000
UNLABELLED BACKGROUND, AIM, AND METHODS: Alpha interferon is the generally approved therapy for HBe antigen positive patients… (More)
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2000
2000
The enzyme IMP dehydrogenase (IMPDH) catalyzes an essential step in the de novo biosynthesis of guanine nucleotides, namely, the… (More)
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1998
1998
BACKGROUND/AIMS The aim of this study was to determine the predictors for sustained response to alpha interferon therapy in a… (More)
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1991
1991
The induction of interferon (IFN) by human immunodeficiency virus type 1 (HIV-1) in primary, nonstimulated monocyte-macrophage… (More)
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Highly Cited
1986
Highly Cited
1986
We treated 10 patients who had chronic non-A,non-B hepatitis with recombinant human alpha interferon in varying doses (0.5 to 5… (More)
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1986
1986
A cooperative study was carried out in 44 institutions in Japan to evaluate the clinical efficacy of two kinds of recombinant… (More)
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