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Interferon Alpha, Human

Known as: Interferon Alfa-N3, Human leukocyte interferon, alfa-n3 interferon 
A class of interferon (leukocyte interferon) produced predominantly by B lymphocytes. Located in a cluster on 9p22 there are at least 13 functional… 
National Institutes of Health

Related topics

Related topics

14 relations
Cytokine GeneCytokine Receptor BindingCytokine SignalingExtracellular Space

Broader (1)

Interferon-alpha

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Characterization of Dendritic Cell-Derived Extracellular Vesicles During Dengue Virus Infection
The dengue virus (DENV), transmitted by Aedes spp. mosquitoes, is one of the most important arboviral infections in the world… 
2017
2017
De-immunized and Functional Therapeutic (DeFT) versions of a long lasting recombinant alpha interferon for antiviral therapy.
2010
2010
Positive Selection of the Bat Interferon Alpha Gene Family
Type I interferons (IFNs) are produced by leukocytes in reaction to pathogenic infection and function as positive mediators in… 
Review
2007
Review
2007
Present role and future potential of type I interferons in adjuvant therapy of high-risk operable melanoma.
2005
2005
A Comparison of the Anti-Luteolytic Activities of Recombinant Ovine Interferon-Alpha and -Tau in Sheep1
Abstract Interferon tau (IFNT) is secreted by the trophectoderm of ruminant conceptuses during the peri-implantation period and… 
1997
1997
The Testicular Antiviral Defense System: Localization, Expression, and Regulation of 2′5′ Oligoadenylate Synthetase, Double-Stranded RNA-activated Protein Kinase, and Mx Proteins in the Rat…
Although the involvement of viruses in alterations of testicular function and in sexually transmitted diseases is well known… 
Review
1995
Review
1995
"Kinoids": the basis for anticytokine immunization and their use in HIV infection.
HIV infection is characterized, at least in part, by the dysregulation of the cytokine network. Both IFN gamma and IFN alpha are… 
Highly Cited
1995
Highly Cited
1995
Vaccinia Virus B18R Gene Encodes a Type I Interferon-binding Protein That Blocks Interferon α Transmembrane Signaling (*)
Poxviruses encode a large number of proteins that attenuate the inflammatory and immune responses to infection. In this report we… 
1992
1992
Correlation between interferon (IFN) alpha resistance and deletion of the IFN alpha/beta genes in acute leukemia cell lines suggests selection against the IFN system.
Homozygous and hemizygous deletions of the interferon A (IFNA) and IFNB genes have been frequently observed in acute leukemia… 
1991
1991
Glycosylation is Required for Coronavirus TGEV to Induce an Efficient Production of IFNα by Blood Mononuclear Cells
Porcine peripheral blood mononuclear cells (PBMC) are induced to produce interferon alpha (IFNα) following in vitro exposure to… 
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