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Infant Acute Lymphoblastic Leukemia

An acute lymphoblastic leukemia that occurs in infancy.
National Institutes of Health

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13 relations
Atypical lymphocyteBone MarrowHematopoietic and Lymphoid CellHematopoietic and Lymphoid Tissue

Papers overview

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Review
2017
Review
2017
Updates in the biology and therapy for infant acute lymphoblastic leukemia
Purpose of review The prognosis for infants less than 12 months of age who are diagnosed with acute lymphoblastic leukemia (ALL… 
2010
2010
Bimodal distribution of genomic MLL breakpoints in infant acute lymphoblastic leukemia treatment
Bimodal distribution of genomic MLL breakpoints in infant acute lymphoblastic leukemia treatment 
2010
2010
Graft-Versus-Leukemia Effect on Infant Lymphoblastic Leukemia Relapsed After Sibling Hematopoietic Stem Cell Transplantation
Introduction Infant acute lymphoblastic leukemia (ALL) is considered a high-risk entity. Patients diagnosed in the first 3 months… 
2006
2006
KIR-incompatible hematopoietic-cell transplantation for poor prognosis infant acute lymphoblastic leukemia.
Little progress has been made in improving the survival of infants with high-risk acute lymphoblastic leukemia (ALL).[1][1],[2][2… 
2006
2006
MLL gene rearrangements have no direct impact on Ara-C sensitivity in infant acute lymphoblastic leukemia and childhood M4/M5 acute myeloid leukemia
The antimetabolite cytosine arabinoside (Ara-C) is a deoxycytidine analog that is used as a therapeutic agent in many leukemia… 
2005
2005
Targeting FLT 3 in primary MLL-gene – rearranged infant acute lymphoblastic leukemia
Acute lymphoblastic leukemia (ALL) in infants is characterized by rearrangements of the mixed lineage leukemia (MLL) gene, drug… 
2003
2003
CD95 (APO‐1/FAS) deficiency in infant acute lymphoblastic leukemia: detection of novel soluble Fas splice variants
Abstract: Fas (APO‐1/CD95) is a 45‐kDa membrane protein which regulates apoptosis in many lymphoid cell types. In the present… 
2002
2002
A novel infant acute lymphoblastic leukemia cell line with MLL-AF5q31 fusion transcript
Infant acute lymphoblastic leukemia (ALL) is characterized by the presence of the proB phenotype (CD10−/CD19+), poor prognosis… 
2001
2001
Presence of N regions in the clonotypic DJ rearrangements of the immunoglobulin heavy-chain genes indicates an exquisitely short latency in t(4;11)-positive infant acute lymphoblastic leukemia.
Childhood acute lymphoblastic leukemia (ALL) is frequently initiated in utero at a time of developmentally regulated insertion of… 
Highly Cited
1999
Highly Cited
1999
AF5q31, a newly identified AF4-related gene, is fused to MLL in infant acute lymphoblastic leukemia with ins(5;11)(q31;q13q23).
Infant acute lymphoblastic leukemia (ALL) with MLL gene rearrangements is characterized by early pre-B phenotype (CD10(-)/CD19… 
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