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Indolizidines

Known as: Indolizidines [Chemical/Ingredient] 
Saturated indolizines that are fused six and five-membered rings with a nitrogen atom at the ring fusion. They are biosynthesized in PLANTS by… 
National Institutes of Health

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(13aS)-deoxytylophorinine3,6,7-trimethoxyphenanthroindolizidineflueggine Bhispiloscine
In Bloodagonistsantagonists & inhibitorsaspects of radiation effects

Papers overview

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2013
2013
NHC-mediated cross-coupling of sugar-derived cyclic nitrones with enals: general and efficient synthesis of polyhydroxylated pyrrolizidines and indolizidines.
A general and efficient method for the synthesis of polyhydroxylated pyrrolizidines and indolizidines has been developed based on… 
2010
2010
The organocatalytic [3+2] cycloaddition of azomethine ylides and alpha,beta-unsaturated aldehydes as a convenient tool for the enantioselective synthesis of pyrrolizidines and indolizidines.
We have developed a simple and straightforward procedure for the enantioselective preparation of densely substituted bicyclic and… 
2010
2010
Stereoselective synthesis of 2,3,6-trisubstituted tetrahydropyridines via Tf(2)O-mediated Grob fragmentation: access to indolizidines (-)-209I and (-)-223J.
Herein we describe the γ-amino hydroxide Grob fragmentation of the aza-bicyclo[2.2.2]octene 1 using triflic anhydride as the… 
2009
2009
Olefin metathesis based approach to diversely functionalized pyrrolizidines and indolizidines; total synthesis of (+)-monomorine.
New scaffolds for the stereoselective synthesis of diversely functionalized chiral enantiopure indolizidines and pyrrolizidines… 
2007
2007
A versatile strategy for divergent and diastereoselective synthesis of natural product-like polyhydroxylated indolizidines.
A general and versatile method for the divergent and diastereoselective synthesis of polyhydroxylated indolizidines has been… 
2005
2005
A one-pot formal [4 + 2] cycloaddition approach to substituted piperidines, indolizidines, and quinolizidines. total synthesis of indolizidine (-)-209I.
[reaction: see text] Heating a mixture of substituted N-benzyl gamma-chloropropylamines, conjugated alkynoates or alkynones… 
2005
2005
A formal [3+2] cycloaddition process with nonactivated aziridines to polysubstituted indolizidines.
[chemical reaction: see text]. Heating a mixture of ethyl 7-iodo-2-heptynoate (or its analogues), 2-aryl aziridines, and K2CO3 in… 
Review
2003
Review
2003
General methods for iminosugar synthesis.
Recent iminosugar syntheses starting both from commercially available sugars and non-glycidic precursors, are reported in this… 
2002
2002
Nitrone dipolar cycloaddition routes to piperidines and indolizidines. Part 9. Formal synthesis of (−)-pinidine and total synthesis of (−)-histrionicotoxin, (+)-histrionicotoxin and…
An intramolecular hydroxylamine-alkyne cyclisation is used for the enantioselective synthesis of the cyclic nitrones 36 and 44… 
Highly Cited
1993
Highly Cited
1993
Alkaloids from bufonid toads (Melanophryniscus): decahydroquinolines, pumiliotoxins and homopumiliotoxins, indolizidines, pyrrolizidines, and quinolizidines.
Skins of bufonid toads of the genus Melanophryniscus contain several classes of alkaloids: decahydroquinolines, pumiliotoxins… 
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