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Indican

Known as: Indoxyl Sulfate, 1H-Indol-3-ol Hydrogen Sulfate Ester, 1H-Indol-3-ol, hydrogen sulfate (ester) 
A substance occurring in the urine of mammals and also in blood plasma as the normal metabolite of tryptophan. An increased urinary excretion of… 
National Institutes of Health

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Indicans

Papers overview

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2015
2015
Indoxyl sulfate upregulates prorenin expression via nuclear factor-κB p65, signal transducer and activator of transcription 3, and reactive oxygen species in proximal tubular cells.
We have recently found that indoxyl sulfate induces prorenin expression in proximal tubular cells. The present study aimed to… 
2013
2013
Anionic metabolic profiling of urine from antibiotic-treated rats by capillary electrophoresis–mass spectrometry
A recently developed capillary electrophoresis (CE)-negative-ionisation mass spectrometry (MS) method was used to profile anionic… 
2012
2012
Effects of indoxyl sulfate on adherens junctions of endothelial cells and the underlying signaling mechanism
Uremic patients have a much higher risk of cardiovascular diseases and death. Uremic toxins are probably involved in the… 
2007
2007
Downregulation of organic anion transporters in rat kidney under ischemia/reperfusion-induced acute [corrected] renal failure.
The effect of acute renal failure (ARF) induced by ischemia/reperfusion (I/R) of rat kidney on the expression of organic anion… 
2004
2004
Spectroscopic characterization of copper(II) complexes of indoxyl N(4)-methyl thiosemicarbazone.
2003
2003
Effects of the oral adsorbent AST-120 on tryptophan metabolism in uremic patients.
BACKGROUND Tryptophan (TRP), an essential amino acid, is bound mostly to albumin in plasma. However, it is reported that binding… 
2000
2000
Decreased Bilirubin-Binding Capacity in Uremic Serum Caused by an Accumulation of Furan Dicarboxylic Acid
In chronic renal failure, substances that are effectively excreted in healthy subjects accumulate in serum. These substances… 
1987
1987
Contributions of hippurate, indoxyl sulfate, and o-hydroxyhippurate to impaired ligand binding by plasma in azotemic humans.
1985
1985
The microbial metabolism of tryptophan in rats fed a diet containing 7.5% saccharin in a two-generation protocol.
1974
1974
The analysis of indolic tryptophan metabolites in human urine. Thin-layer chromatography and in situ quantitation.
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