Indican

Known as: Indoxyl Sulfate, 1H-Indol-3-ol Hydrogen Sulfate Ester, 1H-Indol-3-ol, hydrogen sulfate (ester) 
A substance occurring in the urine of mammals and also in blood plasma as the normal metabolite of tryptophan. An increased urinary excretion of… (More)
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Next-generation sequencing of the hypervariable V3 region of the 16s rRNA gene isolated from serial stool specimens collected… (More)
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Highly Cited
2010
Highly Cited
2010
The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor involved in the regulation of multiple cellular… (More)
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Highly Cited
2010
Highly Cited
2010
AIMS Indoxyl sulfate (IS) is a uraemic toxin found at high concentration in patients with chronic kidney disease (CKD) co-morbid… (More)
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Highly Cited
2009
Highly Cited
2009
Although it has long been recognized that the enteric community of bacteria that inhabit the human distal intestinal track… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND AND OBJECTIVES As a major component of uremic syndrome, cardiovascular disease is largely responsible for the high… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Endothelial dysfunction and oxidative stress are matters of concern in patients with chronic renal failure (CRF… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Chronic renal failure patients are at high risk of cardiovascular events and display endothelial dysfunction, a… (More)
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Review
2006
Review
2006
Renal failure not only alters the renal elimination, but also the non-renal disposition of drugs that are extensively metabolized… (More)
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Highly Cited
2002
Highly Cited
2002
In uremic patients, various uremic toxins are accumulated and exert various biologic effects on uremia. Indoxyl sulfate (IS) is… (More)
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Review
2001
Review
2001
Although it was originally believed that thyroid hormones enter target cells by passive diffusion, it is now clear that cellular… (More)
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