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Immunoglobulin Class Switch Recombination

Known as: Immunoglobulin Isotype-Switch Recombination, Immunoglobulin Switch Recombination, Switch Recombination 
Any process of gene rearrangement in which one immunoglobulin heavy chain constant coding region is exchanged for another, with the loss of the… 
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
The class and effector functions of antibodies are modulated through the process of Ig heavy chain class switch recombination… 
Highly Cited
2005
Highly Cited
2005
Class switch recombination was the last of the lymphocyte-specific DNA modification reactions to appear in the evolution of the… 
Highly Cited
2003
Highly Cited
2003
Nucleotide substitutions are found in recombined Ig switch (S) regions and also in unrecombined (germline, GL) Sμ segments in… 
Highly Cited
2001
Highly Cited
2001
The isotype specificity of immunoglobulin (Ig) class switching is regulated by a cytokine which induces transcription of a… 
Review
1999
Review
1999
A DAPTIVE IMMUNITY in mammals depends on the generation of a vast repertoire of Ig and T-cell receptor (TCR) specificities… 
Highly Cited
1991
Highly Cited
1991
H chain isotype switch recombination is preceded by the appearance of RNA initiating 5' of the specific switch region that will… 
Review
1986
Review
1986
The comparative analysis of Ig class switch recombination in a priori IgG/IgA-expressing myelomas and hybridomas, in switch… 
Highly Cited
1982
Highly Cited
1982
Immunoglobin heavy (H) chains are composed of a variable (VH) and a constant (CH) region. The latter is encoded respectively by…