Imipenem

Known as: (5R,6S)-3-((2-(Formimidoylamino)ethyl)thio)-6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, Imipenem [Chemical/Ingredient], Imipenem, n-formimidoyl thienamycin 
A broad-spectrum, semi-synthetic beta-lactam carbapenem derived from thienamycin, produced by Streptomyces cattleya. Imipenem binds to and… (More)

Topic mentions per year

Topic mentions per year

1957-2018
020040060019572017

Papers overview

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Highly Cited
2004
Highly Cited
2004
Klebsiella pneumoniae strain 11978 was isolated in Turkey in 2001 and was found to be resistant to all beta-lactams, including… (More)
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Highly Cited
2003
Highly Cited
2003
We prospectively evaluated the efficacy and toxicity of intravenously administered colistin in 35 episodes of ventilator… (More)
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Highly Cited
2003
Highly Cited
2003
Gram-negative bacilli with acquired metallo-beta-lactamase (MBL) production have been increasingly reported in some countries… (More)
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Highly Cited
2002
Highly Cited
2002
Rapid detection of metallo-beta-lactamase (MBL)-producing gram-negative bacilli is necessary to prevent their dissemination. The… (More)
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Highly Cited
2001
Highly Cited
2001
A Klebsiella pneumoniae isolate showing moderate to high-level imipenem and meropenem resistance was investigated. The MICs of… (More)
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Highly Cited
1998
Highly Cited
1998
The general view that mRNA does not contain inosine has been challenged by the discovery of adenosine deaminases that act on RNA… (More)
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Highly Cited
1997
Highly Cited
1997
Six Escherichia coli and 12 Klebsiella pneumoniae isolates from a single hospital expressed a common beta-lactamase with a pI of… (More)
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Highly Cited
1993
Highly Cited
1993
Recent evidence of pancreatic penetration of several antibiotics active against the usual flora found in pancreatic sepsis, at… (More)
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Highly Cited
1991
Highly Cited
1991
We isolated an imipenem-resistant strain, GN17203, of Pseudomonas aeruginosa. The strain produced a beta-lactamase that… (More)
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Highly Cited
1987
Highly Cited
1987
This study evaluated the sensitivity of mitochondrial respiratory control as a function of tissue oxidative capacity. The… (More)
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