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Imipenem

Known as: (5R,6S)-3-((2-(Formimidoylamino)ethyl)thio)-6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, Imipenem [Chemical/Ingredient], Imipenem, n-formimidoyl thienamycin 
A broad-spectrum, semi-synthetic beta-lactam carbapenem derived from thienamycin, produced by Streptomyces cattleya. Imipenem binds to and… 
National Institutes of Health

Related topics

Related topics

28 relations

Broader (1)

Anti-Bacterial Agents
Bacterial EndocarditisBacterial InfectionsCarbapenemsCilastatin 250 MG / Imipenem 250 MG Injection [Primaxin]

Narrower (4)

Cilastatin / ImipenemMK-0787Primaxinxanthoradone C

Papers overview

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Highly Cited
2006
Highly Cited
2006
Antimicrobial resistance in food and clinical Aeromonas isolates.
Highly Cited
2002
Highly Cited
2002
Skin and soft tissue infections in Latin American medical centers: four-year assessment of the pathogen frequency and antimicrobial susceptibility patterns.
Highly Cited
1998
Highly Cited
1998
Antibiotic sensitization using biphenyl tetrazoles as potent inhibitors of Bacteroides fragilis metallo-beta-lactamase.
Highly Cited
1992
Highly Cited
1992
Metabolic changes with fatigue in different types of single muscle fibres of Xenopus laevis.
1. Peak isometric force of single fast (type 1) and slow (type 3) muscle fibres of Xenopus decreased when fibres were stimulated… 
Highly Cited
1991
Highly Cited
1991
Carbohydrate supplementation attenuates IMP accumulation in human muscle during prolonged exercise.
The effect of carbohydrate (CHO) ingestion on metabolic responses to exercise has been investigated. Subjects cycled at… 
Highly Cited
1985
Highly Cited
1985
Influence of aerobic metabolism on IMP accumulation in fast-twitch muscle.
Significant activation of AMP deaminase in fast-twitch muscle leads to a loss of ATP and accumulation of NH4 and IMP. Although… 
Highly Cited
1979
Highly Cited
1979
Differences in ammonia and adenylate metabolism in contracting fast and slow muscle.
The time course of AMP deamination and IMP reamination was studied during in situ stimulation and subsequent recovery in fast… 
Highly Cited
1979
Highly Cited
1979
N-Acetimidoyl- and N-formimidoylthienamycin derivatives: antipseudomonal beta-lactam antibiotics.
Highly Cited
1976
Highly Cited
1976
Control of energy metabolism in fish white muscle.
Concentrations of key metabolites were determined in carp white muscle before exercise and after maximal activity. It was found… 
Highly Cited
1969
Highly Cited
1969
Human hypoxanthine phosphoribosyltransferase. I. Purification, properties, and specificity.
Abstract Hypoxanthine phosphoribosyltransferase (inosine monophosphate:pyrophosphate phosphoribosyltransferase EC 2.4.2.8) has… 
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