Skip to search formSkip to main contentSkip to account menu

Imipenem

Known as: (5R,6S)-3-((2-(Formimidoylamino)ethyl)thio)-6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, Imipenem [Chemical/Ingredient], Imipenem, n-formimidoyl thienamycin 
A broad-spectrum, semi-synthetic beta-lactam carbapenem derived from thienamycin, produced by Streptomyces cattleya. Imipenem binds to and… 
National Institutes of Health

Related topics

Related topics

28 relations

Broader (1)

Anti-Bacterial Agents
Bacterial EndocarditisBacterial InfectionsCarbapenemsCilastatin 250 MG / Imipenem 250 MG Injection [Primaxin]

Narrower (4)

Cilastatin / ImipenemMK-0787Primaxinxanthoradone C

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1986
Highly Cited
1986
Postantibiotic effect of imipenem on gram-positive and gram-negative micro-organisms.
The bactericidal effect (BE) of an antibiotic reduces the infective population, and its postantibiotic effect (PAE) assures a… 
1986
1986
Imipenem pharmacokinetics and body fluid concentrations in patients receiving high-dose treatment for serious infections
Serum, urine, tissue, and body fluids were collected from 40 adult patients who were receiving imipenem/cilastatin treatment for… 
1982
1982
Lack of in vivo and in vitro bactericidal activity of N-formimidoyl thienamycin against enterococci
The minimal bactericidal concentrations of N-formimidoyl thienamycin (N-f-thienamycin) against 21 strains of enterococci isolated… 
1982
1982
In vitro susceptibility of Mycobacterium fortuitum to N-formimidoyl thienamycin and several cephamycins
The comparative in vitro activity of N-formimidoyl thienamycin, cefmetazole, cefoxitin, cefotetan (YM-09330), and moxalactam… 
1982
1982
Comparative activities of N-formimidoyl thienamycin, ticarcillin, and tobramycin against experimental Pseudomonas aeruginosa pneumonia
The therapeutic efficacies of disodium ticarcillin, tobramycin sulfate, and N-formimidoyl thienamycin (MK0787) were compared in… 
Highly Cited
1981
Highly Cited
1981
In vitro activity of N-formimidoyl thienamycin, moxalactam, and other new beta-lactam agents against Bacteroides fragilis: contribution of beta-lactamase to resistance
N-Formimidoyl thienamycin (N-F-thienamycin) and moxalactam were compared with other currently available and investigational… 
1981
1981
In vitro activity of N-formimidoyl thienamycin (MK0787) against resistant strains of Pseudomonas aeruginosa, Staphylococcus epidermidis, Serratia marcescens, and Enterococcus spp
The in vitro activities of N-formimidoyl thienamycin (MK0787) and nine other antibiotics were tested against 129 clinical… 
1980
1980
Effect of N-formimidoyl thienamycin (MK0787) on beta-lactamases and activity against beta-lactamase-producing strains
N-Formimidoyl thienamycin (MK0787) was active against beta-lactamase-producing strains and was an effective inhibitor of beta… 
1974
1974
Comparison of adaptations to diet of enzymes involved in uric acid production from IMP in chickens and rats.
Highly Cited
1969
Highly Cited
1969
Inhibition of 5'-nucleotidase from Ehrlich ascites-tumour cells by nucleoside triphosphates.
1. 5'-Nucleotidase activity was obtained in a soluble form after treatment of a particulate fraction from Ehrlich ascites-tumour…