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IkappaB Kinase epsilon

Known as: IKK epsilon, IKKepsilon, Kinase epsilon, IkappaB 
National Institutes of Health

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Related topics

2 relations
IKBKE gene

Broader (1)

IkappaB kinase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Predicting and validating a model of suppressor of IKKepsilon through biophysical characterization
Suppressor of IKKepsilon (SIKE) is a 207 residue protein that is implicated in the TLR3‐TANK‐binding kinase‐1‐mediated response… 
Review
2011
Review
2011
IKKε: A Kinase at the Intersection of Signaling and Membrane Traffic
IKKε-mediated phosphorylation events may redirect endosomal traffic by switching the motor proteins associated with vesicles. The… 
2011
2011
Characterization of IKBKE as a Breast Cancer Oncogene
Abstract : Previous work in the Hahn Lab has identified IKBKE as a novel breast cancer oncogene that is capable of human mammary… 
2009
2009
Over‐expression of IκB‐kinase‐ε (IKKε/IKKi) induces secretion of inflammatory cytokines in prostate cancer cell lines
Elevated inflammatory cytokine levels in serum have been associated with advanced stage metastasis‐related morbidity in prostate… 
Highly Cited
2007
Highly Cited
2007
Involvement of TBK1 and IKKϵ in lipopolysaccharide‐induced activation of the interferon response in primary human macrophages
Interferon (IFN) is an important effector of the innate immune response, induced by different viral or bacterial components… 
2007
2007
All roads lead to IKKepsilon.
Extensive genetic alterations have been found in many epithelial malignancies. Using three complementary genetic approaches… 
2006
2006
TNF-alpha and IFN-alpha enhance influenza-A-virus-induced chemokine gene expression in human A549 lung epithelial cells.
Lung epithelial cells are the primary cellular targets for respiratory virus pathogens such as influenza and parainfluenza… 
Review
2006
Review
2006
The kinase complex responsible for IRF-3-mediated IFN-beta production in myeloid dendritic cells (mDC).
Type I interferons (IFN) IFN-alpha and -beta play a central role in the induction of antiviral immunity, which involves up… 
2005
2005
Genomic structure and functional characterization of the promoter region of human IkappaB kinase-related kinase IKKi/IKKvarepsilon gene.
The inducible IkappaB kinase (IKKi/IKKepsilon) is a recently described serine-threonine kinase that activates the transcription… 
2003
2003
NF-kappaB induction by bisperoxovanadium compounds requires CD45, p36(LAT), PKC, and IKK activity and exhibits kinetics of activation comparable to those of TCR/CD28 coengagement.
We have previously shown that bisperoxovanadium (bpV) phosphotyrosyl phosphatase inhibitors can potently activate NF-kappaB. We… 
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