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IkappaB Kinase epsilon

Known as: IKK epsilon, IKKepsilon, Kinase epsilon, IkappaB 
National Institutes of Health

Related topics

Related topics

2 relations
IKBKE gene

Broader (1)

IkappaB kinase

Papers overview

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Highly Cited
2009
Highly Cited
2009
Severe Acute Respiratory Syndrome Coronavirus M Protein Inhibits Type I Interferon Production by Impeding the Formation of TRAF3·TANK·TBK1/IKKϵ Complex*
Severe acute respiratory syndrome (SARS) coronavirus is highly pathogenic in humans and evades innate immunity at multiple levels… 
Highly Cited
2009
Highly Cited
2009
Deregulation of IKBKE is associated with tumor progression, poor prognosis, and cisplatin resistance in ovarian cancer.
I-kappa-B kinase e (IKBKE; IKKepsilon) has been recently identified as a breast cancer oncogene, and its alteration appears to be… 
Highly Cited
2008
Highly Cited
2008
Regulation of IκB Kinase-related Kinases and Antiviral Responses by Tumor Suppressor CYLD*
The IκB kinase (IKK)-related kinases, IKKϵ and TBK1, participate in the induction of type I interferons (IFNs) during viral… 
Highly Cited
2008
Highly Cited
2008
Measles Virus V Protein Is a Decoy Substrate for IκB Kinase α and Prevents Toll-Like Receptor 7/9-Mediated Interferon Induction
ABSTRACT The central role of plasmacytoid dendritic cells (pDC) in activating host immune responses stems from their high… 
Highly Cited
2007
Highly Cited
2007
Multiple functions of the IKK-related kinase IKKepsilon in interferon-mediated antiviral immunity.
IKKepsilon is an IKK (inhibitor of nuclear factor kappaBkinase)-related kinase implicated in virus induction of interferon-beta… 
Highly Cited
2006
Highly Cited
2006
Toll-like Receptor-dependent and -independent Viperin Gene Expression and Counter-regulation by PRDI-binding Factor-1/BLIMP1*
Here we identify Viperin as a highly inducible gene in response to lipopolysaccharide (LPS), double-stranded RNA (poly(I-C)) or… 
Highly Cited
2006
Highly Cited
2006
Inducible Phosphorylation of NF-κB p65 at Serine 468 by T Cell Costimulation Is Mediated by IKKϵ*
Here we identify IKKϵ as a novel NF-κB p65 kinase that mediates inducible phosphorylation of Ser468 and Ser536 in response to T… 
Highly Cited
2006
Highly Cited
2006
Induction of IRF-3 and IRF-7 phosphorylation following activation of the RIG-I pathway.
The induction of type I interferon (IFN) and the development of the innate antiviral response are mediated by the activation of… 
Highly Cited
2005
Highly Cited
2005
Nuclear Localization of the Nipah Virus W Protein Allows for Inhibition of both Virus- and Toll-Like Receptor 3-Triggered Signaling Pathways
ABSTRACT The Nipah virus V and W proteins, which are encoded by the P gene via RNA editing, have a common N-terminal domain but… 
Highly Cited
2004
Highly Cited
2004
Mechanisms of the TRIF-induced Interferon-stimulated Response Element and NF-κB Activation and Apoptosis Pathways*
Toll-like receptor-3 is critically involved in host defense against viruses through induction of type I interferons (IFNs… 
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