IgG2b location

Cellular Fcγ receptors are essential for IgG-dependent effector functions in vivo. There is convincing evidence that selective… (More)

The relative ability of IgG subclasses to cause acute inflammation and the roles of specific effector mechanisms in this process… (More)

Beta-amyloid (Abeta) peptide has been proposed to be a causal factor in Alzheimer's disease (AD). Currently being investigated… (More)

Alloantibodies (AlloAbs) are a clinically significant component of the immune response to organ transplants. In our experimental… (More)

By generating four IgG isotype-switch variants of the high affinity 34-3C anti-erythrocyte autoantibody, and comparing them to… (More)

LPS was used to induce switching of B cells to IgG3 and, in the presence of TGF-beta, to IgG2b and IgA. Switching to all three… (More)

We assessed the in vivo anti-tumor effectiveness of monoclonal antibodies of different isotypes. Starting with a hybridoma cell… (More)

Methods for the production and purification of F(ab')2 fragments from BALB/c monoclonal IgG1, IgG2a, and IgG2b with pepsin and… (More)

The effect of T lymphocytes on the IgM, IgG3, IgG1, IgG2b, and IgG2a responses of B lymphocytes to the type-2 T-independent… (More)

The specificity of Fe-receptors on IC-21 cells, an established line of mouse peritoneal macrophages with antibody-dependent… (More)