Idarubicin

Known as: Idarubicin [Chemical/Ingredient], 4 Desmethoxydaunorubicin, (1S,3S)-3-Acetyl-1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-6,11-dioxo-1-naphthacenyl-3-amino-2,3,6-trideoxy-alpha-L-hexopyranoside 
A semisynthetic 4-demethoxy analogue of the antineoplastic anthracycline antibiotic daunorubicin. Idarubicin intercalates into DNA and interferes… (More)
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
BACKGROUND All-trans retinoic acid (ATRA) with chemotherapy is the standard of care for acute promyelocytic leukemia (APL… (More)
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Highly Cited
2011
Highly Cited
2011
We conducted a multi-institutional randomized study to determine whether high-dose daunorubicin would be as effective as standard… (More)
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Highly Cited
2010
Highly Cited
2010
PURPOSE To determine the efficacy and toxicity of the combination of sorafenib, cytarabine, and idarubicin in patients with acute… (More)
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Highly Cited
2009
Highly Cited
2009
PURPOSE To compare the antitumor efficacy of three different anthracyclines in combination with cytarabine and etoposide in adult… (More)
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Highly Cited
2008
Highly Cited
2008
An understanding of the prognostic factors associated with the various forms of induction mortality in patients with acute… (More)
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Highly Cited
2001
Highly Cited
2001
It has been unclear whether regimens containing topotecan + ara-C (TA) or fludarabine + ara-C (FA) +/- idarubicin are superior to… (More)
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Highly Cited
1997
Highly Cited
1997
By Franco Mandelli, Daniela Diverio, Giuseppe Avvisati, Anna Luciano, Tiziano Barbui, Carlo Bernasconi, Giorgio Broccia… (More)
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Highly Cited
1997
Highly Cited
1997
Two hundred fifty-three patients with newly diagnosed acute promyelocytic leukemia (APL) were eligible to enter the multicentric… (More)
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Highly Cited
1992
Highly Cited
1992
The purpose of this study was to determine the relative merits of idarubicin and daunorubicin in acute myeloid leukemia (AML… (More)
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Highly Cited
1992
Highly Cited
1992
PURPOSE A randomized clinical trial was undertaken to compare the therapeutic effectiveness of idarubicin (IDR) to daunorubicin… (More)
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