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Idarubicin

Known as: Idarubicin [Chemical/Ingredient], 4 Desmethoxydaunorubicin, (1S,3S)-3-Acetyl-1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-6,11-dioxo-1-naphthacenyl-3-amino-2,3,6-trideoxy-alpha-L-hexopyranoside 
A semisynthetic 4-demethoxy analogue of the antineoplastic anthracycline antibiotic daunorubicin. Idarubicin intercalates into DNA and interferes… Expand
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Helicobacter pylori (H. pylori) infection is very common and affects approximately half of the world population. It causes… Expand
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Highly Cited
2013
Highly Cited
2013
BACKGROUND All-trans retinoic acid (ATRA) with chemotherapy is the standard of care for acute promyelocytic leukemia (APL… Expand
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Highly Cited
2010
Highly Cited
2010
PURPOSE To determine the efficacy and toxicity of the combination of sorafenib, cytarabine, and idarubicin in patients with acute… Expand
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Highly Cited
2009
Highly Cited
2009
The anemia of chronic disease (ACD) is characterized by macrophage iron retention induced by cytokines and the master regulator… Expand
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Highly Cited
2008
Highly Cited
2008
An understanding of the prognostic factors associated with the various forms of induction mortality in patients with acute… Expand
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Highly Cited
2003
Highly Cited
2003
Approximately 20–30% of patients with acute promyelocytic leukemia (APL) who are treated with all‐trans retinoic acid (ATRA) and… Expand
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Highly Cited
1998
Highly Cited
1998
A joint Task Group of ICRP Committees 2 (Doses from Radiation Exposures) and 3 (Protection in Medicine; lead Committee for this… Expand
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Highly Cited
1997
Highly Cited
1997
Two hundred fifty-three patients with newly diagnosed acute promyelocytic leukemia (APL) were eligible to enter the multicentric… Expand
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Highly Cited
1997
Highly Cited
1997
The immune-mediated graft-versus-leukemia effect is important to prevent relapse after allogeneic progenitor cell transplantation… Expand
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Highly Cited
1992
Highly Cited
1992
The purpose of this study was to determine the relative merits of idarubicin and daunorubicin in acute myeloid leukemia (AML… Expand
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