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Idarubicin

Known as: Idarubicin [Chemical/Ingredient], 4 Desmethoxydaunorubicin, (1S,3S)-3-Acetyl-1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-6,11-dioxo-1-naphthacenyl-3-amino-2,3,6-trideoxy-alpha-L-hexopyranoside 
A semisynthetic 4-demethoxy analogue of the antineoplastic anthracycline antibiotic daunorubicin. Idarubicin intercalates into DNA and interferes… 
National Institutes of Health

Related topics

Related topics

44 relations
10 ML Idarubicin Hydrochloride 1 MG/ML InjectionAIE RegimenAnthracyclinesCOG-C9710 APL Regimen

Narrower (23)

13-methyl-13-dihydro-4-demethoxydaunorubicin4-demethoxy-10,10-dimethyldaunomycin4-demethoxy-11-deoxydaunomycin4-demethoxydaunomycinone

Broader (1)

Antibiotics, Antineoplastic

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Better outcome of adult acute lymphoblastic leukemia after early genoidentical allogeneic bone marrow transplantation (BMT) than after late high-dose therapy and autologous BMT: a GOELAMS trial.
Various transplantation strategies have been designed to improve the poor prognosis of adult (ages 15 to 60 years) acute… 
Highly Cited
2004
Highly Cited
2004
The effects of iron deficiency on infants' developmental test performance
Aim: To assess the effects of iron deficiency on developmental test scores in infants. Methods: This prospective, single‐blind… 
Highly Cited
1999
Highly Cited
1999
Randomized phase II study of fludarabine + cytosine arabinoside + idarubicin +/- all-trans retinoic acid +/- granulocyte colony-stimulating factor in poor prognosis newly diagnosed acute myeloid…
Preclinical data suggest that retinoids, eg, all-trans retinoic acid (ATRA), lower concentrations of antiapoptotic proteins such… 
Review
1998
Review
1998
Clinical applications of anticancer drugs targeted to topoisomerase II.
Highly Cited
1998
Highly Cited
1998
Diffusion-weighted MR imaging of the hippocampus and temporal white matter in Alzheimer's disease
Highly Cited
1995
Highly Cited
1995
Bulk density of asteroid 243 Ida from the orbit of its satellite Dactyl
DURING its reconnaissance of the asteroid 243 Ida, the Galileo spacecraft returned images of a second object, 1993(243)1 Dactyl1… 
Highly Cited
1994
Highly Cited
1994
Thyroid volume measurement by ultrasound in children as a tool for the assessment of mild iodine deficiency.
Thyroid ultrasound was used to measure thyroid volume in children and compared with thyroid palpation for the assessment of the… 
Review
1994
Review
1994
Iron deficiency: the global perspective.
The prevelance of IDA in industrialized countries has declined in recent decades, but there has been little change in the… 
Highly Cited
1991
Highly Cited
1991
Results of a randomized trial comparing idarubicin and cytosine arabinoside with daunorubicin and cytosine arabinoside in adult patients with newly diagnosed acute myelogenous leukemia
4'-Demethoxydaunorubicin (idarubicin [IDR]) is a new anthracycline that differs from its parent compound by the deletion of a… 
Highly Cited
1947
Highly Cited
1947
DISEASE
Background: Little is known about patients who frequently visit the emergency department (ED) for acute exacerbation of chronic… 
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