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Icrucumab

Known as: Anti-VEGFR-1 Monoclonal Antibody IMC-18F1, Anti-Vascular Endothelial Growth Factor Receptor-1 Monoclonal Antibody IMC-18F1 
A fully human IgG1 monoclonal antibody directed against human vascular endothelial growth factor receptor 1 (VEGFR-1/FLT-1) with potential… Expand
National Institutes of Health

Papers overview

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2017
2017
Vascular endothelial growth factor (VEGF) signaling is tightly regulated by specific VEGF receptors (VEGF-R). Recently, we… Expand
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2017
2017
BACKGROUND Icrucumab (ICR) and ramucirumab (RAM) bind vascular endothelial growth factor (VEGF) receptors 1 and 2 (VEGFR-1 and -2… Expand
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Highly Cited
2016
Highly Cited
2016
PURPOSE This trial assessed the efficacy and safety of docetaxel monotherapy or docetaxel in combination with ramucirumab… Expand
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2016
2016
BACKGROUND Icrucumab and ramucirumab are recombinant human IgG1 monoclonal antibodies that bind VEGF receptors 1 and 2 (VEGFR-1… Expand
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2015
2015
295 Background: Patients (pts) with metastatic urothelial carcinoma (UC) progressing after first-line chemotherapy have limited… Expand
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2013
2013
SummaryBackground IMC-18F1 (icrucumab), a human monoclonal antibody against vascular endothelial growth factor receptor-1 (VEGFR… Expand
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2012
2012
TPS4675^ Background: The vascular endothelial growth factor (VEGF) pathway may play an important role in the pathogenesis of… Expand
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2007
2007
BACKGROUND Vascular endothelial growth factor (VEGF), originally identified as an endothelium-specific factor, can also bind to… Expand
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2005
2005
OBJECTIVE Evaluation of the role of VEGF in cartilage pathophysiology. METHODS VEGF release from chondrocytes in the presence… Expand
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2003
2003
OBJECTIVES The aim of this study was to investigate the prognostic value of vascular endothelial growth factor (VEGF) receptors… Expand
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