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Icrucumab

Known as: Anti-VEGFR-1 Monoclonal Antibody IMC-18F1, Anti-Vascular Endothelial Growth Factor Receptor-1 Monoclonal Antibody IMC-18F1 
A fully human IgG1 monoclonal antibody directed against human vascular endothelial growth factor receptor 1 (VEGFR-1/FLT-1) with potential… 
National Institutes of Health

Related topics

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4 relations
Antibody-Dependent Cellular CytotoxicityNCIt Antineoplastic Agent Terminologyantigen binding

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IMC-18F1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Імуногістохімічна характеристика експресії VEGF-A, VEGFR-1, VEGFR-2 і CD34 при прогресуванні колоректальної аденокарциноми
Aim – to study VEGF-A, VEGFR-1, VEGFR-2 and CD34 immunohistochemical expression on the I, II, III, IV stages (pTNM) of colorectal… 
2015
2015
Interim results of a randomized phase 2 study of docetaxel with ramucirumab versus docetaxel in second-line advanced or metastatic urothelial carcinoma.
295 Background: Patients (pts) with metastatic urothelial carcinoma (UC) progressing after first-line chemotherapy have limited… 
2013
2013
Avaliação dos fatores de crescimento endotelial vascular VEGF e de seus principais receptores VEGFR-1 e -2 no processo de cicatrização com influência da radioterapia em ratos da linhagem Wistar
2012
2012
Randomized phase II study of docetaxel with or without ramucirumab (IMC-1121B) or icrucumab (IMC-18F1) in patients with urothelial transitional cell carcinoma (TCC) following progression on first…
TPS4675^ Background: The vascular endothelial growth factor (VEGF) pathway may play an important role in the pathogenesis of… 
2007
2007
Epithelial expression of VEGF receptors in colorectal carcinomas and their relationship to metastatic status.
BACKGROUND Vascular endothelial growth factor (VEGF), originally identified as an endothelium-specific factor, can also bind to… 
2005
2005
Vascular endothelial growth factor activities on osteoarthritic chondrocytes.
OBJECTIVE Evaluation of the role of VEGF in cartilage pathophysiology. METHODS VEGF release from chondrocytes in the presence… 
Highly Cited
2002
Highly Cited
2002
Expression of vascular endothelial growth factor (VEGF) and its receptors (Flt-1 and Flk-1) in esophageal squamous cell carcinoma.
BACKGROUND To clarify the clinical significance of vascular endothelial growth factor (VEGF) and its receptors, VEGFR-1 (Flt-1… 
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