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Ichthyoses

Known as: Ichthyotic skin, ICHTHYOSIS, Hypertrophic ichthyosis 
Any of several generalized skin disorders characterized by dryness, roughness, and scaliness, due to hypertrophy of the stratum corneum epidermis… 
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Recently, loss-of-function mutations in FLG, the human gene encoding profilaggrin and filaggrin, have been identified as the… 
Review
2008
Review
2008
Abstract:  The skin forms an effective barrier between the organism and the environment preventing invasion of pathogens and… 
Highly Cited
2007
Highly Cited
2007
We recently reported two common filaggrin (FLG) null mutations that cause ichthyosis vulgaris and predispose to eczema and… 
Review
2006
Review
2006
Ichthyosis vulgaris (OMIM 146700) is the most common inherited disorder of keratinization and one of the most frequent single… 
Review
2006
Review
2006
The ‘acid mantle’ of the stratum corneum seems to be important for both permeability barrier formation and cutaneous… 
Review
2005
Review
2005
The epidermis functions as a barrier against the environment by means of several layers of terminally differentiated, dead… 
Review
2003
Review
2003
The primary function of the epidermis is to produce the protective, semi-permeable stratum corneum that permits terrestrial life… 
Review
2000
Review
2000
DNA damage is implicated in cancer and aging, and several DNA repair mechanisms exist that safeguard the genome from these…