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Ichthyoses

Known as: Ichthyotic skin, ICHTHYOSIS, Hypertrophic ichthyosis 
Any of several generalized skin disorders characterized by dryness, roughness, and scaliness, due to hypertrophy of the stratum corneum epidermis… 
National Institutes of Health

Related topics

Related topics

46 relations
Cardio-facio-cutaneous syndromeCerebral dysgenesis, neuropathy, ichthyosis, and palmoplantar keratoderma syndromeChondrodysplasia punctata, X-linked dominant typeCongenital ichthyosis

Narrower (23)

Congenital Nonbullous Ichthyosiform ErythrodermaDykes Markes Harper syndromeErythrokeratoderma, ReticularGrover's disease

Broader (3)

Dermatologic disordersKeratinization, functionTyloma

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Loss of corneodesmosin leads to severe skin barrier defect, pruritus, and atopy: unraveling the peeling skin disease.
Highly Cited
2009
Highly Cited
2009
Filaggrin deficiency confers a paracellular barrier abnormality that reduces inflammatory thresholds to irritants and haptens.
Highly Cited
2002
Highly Cited
2002
Elevated stratum corneum hydrolytic activity in Netherton syndrome suggests an inhibitory regulation of desquamation by SPINK5-derived peptides.
Netherton syndrome is a congenital ichthyosis associated with erythroderma, hair shaft defects, and atopic features. The… 
Highly Cited
1995
Highly Cited
1995
Mutations of keratinocyte transglutaminase in lamellar ichthyosis
Lamellar ichthyosis is a severe congenital skin disorder characterized by generalized large scales and variable redness. Affected… 
Review
1993
Review
1993
Barrier function regulates epidermal lipid and DNA synthesis
The stratum corneum, the permeability barrier between the internal milieu and the environment, is composed of fibrous protein… 
Highly Cited
1991
Highly Cited
1991
X-linked lymphoreticular disease in the scurfy (sf) mutant mouse.
Scurfy (sf) is a spontaneous, sex-linked, recessive mutation that maps to the extreme proximal portion of the X chromosome, about… 
Highly Cited
1987
Highly Cited
1987
Cloning and expression of steroid sulfatase cDNA and the frequent occurrence of deletions in STS deficiency: Implications for X-Y interchange
Highly Cited
1987
Highly Cited
1987
Melanoma, growth factors, acanthosis nigricans, the sign of Leser-Trélat, and multiple acrochordons. A possible role for alpha-transforming growth factor in cutaneous paraneoplastic syndromes.
CARCINOMAS have been associated with such paraneoplastic syndromes as skin-tumor growth, ectopic hormone production… 
Highly Cited
1985
Highly Cited
1985
Ichthyosis vulgaris: identification of a defect in synthesis of filaggrin correlated with an absence of keratohyaline granules.
Ichthyosis vulgaris is an autosomal dominant disorder of keratinization characterized histologically by absent or reduced… 
Highly Cited
1982
Highly Cited
1982
Interaction of granule, Purkinje and inferior olivary neurons in lurcher chimeric mice. II. Granule cell death
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