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Keratinization, function

Known as: cornification, keratinization 
The process in which the cytoplasm of the outermost cells of the vertebrate epidermis is replaced by keratin. Keratinization occurs in the stratum… 
National Institutes of Health

Related topics

Related topics

49 relations

Narrower (13)

AcrokeratosisCornification, functionHaxthausen's syndromeIchthyoses
Acrokeratosis Verruciformis of HopfBullous pemphigoidCongenital Nonbullous Ichthyosiform ErythrodermaCongenital ichthyosis

Broader (3)

Dermatologic disordersHistogenic Processkeratinocyte differentiation

Papers overview

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Highly Cited
2001
Highly Cited
2001
Generation of free fatty acids from phospholipids regulates stratum corneum acidification and integrity.
There is evidence that the "acid mantle" of the stratum corneum is important for both permeability barrier formation and… 
Highly Cited
1999
Highly Cited
1999
Mutations in ATP2A2, encoding a Ca2+ pump, cause Darier disease
Darier disease (DD) is an autosomal-dominant skin disorder characterized by loss of adhesion between epidermal cells… 
Highly Cited
1996
Highly Cited
1996
Genes encoding structural proteins of epidermal cornification and S100 calcium-binding proteins form a gene complex ("epidermal differentiation complex") on human chromosome 1q21.
Chromosome 1 reveals in region 1q21 a most remarkable density of genes that fulfill important functions in terminal… 
Highly Cited
1995
Highly Cited
1995
Undifferentiated, nonkeratinizing, and squamous cell carcinoma of the nasopharynx. Variants of Epstein-Barr virus-infected neoplasia.
Nasopharyngeal carcinoma (NPC) samples of distinct histological types, including squamous cell carcinoma (WHO type 1… 
Highly Cited
1991
Highly Cited
1991
Epidermal growth factor replaces estrogen in the stimulation of female genital-tract growth and differentiation.
The in vivo studies presented here demonstrate that epidermal growth factor (EGF) is an important autocrine and/or paracrine… 
Highly Cited
1987
Highly Cited
1987
Retinoids as important regulators of terminal differentiation: examining keratin expression in individual epidermal cells at various stages of keratinization
When human epidermal cells were seeded on floating rafts of collagen and fibroblasts, they stratified at the air-liquid interface… 
Highly Cited
1980
Highly Cited
1980
Long-term effects on the female mouse genital tract associated with prenatal exposure to diethylstilbestrol.
Abstract The association between treatment of pregnant women with diethylstilbestrol (DES) and reproductive tract abnormalities… 
Highly Cited
1977
Highly Cited
1977
Blood Vessels
This excellent monograph by Phillippe Sengel brings together an enormous body of data on the embryonic development of the skin in… 
Highly Cited
1974
Highly Cited
1974
Epidermal growth factor: effects of androgens and adrenergic agents.
Epidermal growth factor (EGF) is a polypeptide extracted from male mouse submaxillary glands which promotes epidermal growth and… 
Highly Cited
1965
Highly Cited
1965
The stimulation of epidermal proliferation by a specific protein (EGF).
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