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ITGA5 protein, human

Known as: VLA5, CD49 Antigen-Like Family Member E, Integrin Alpha-5 
Integrin alpha-5 (1049 aa, ~115 kDa) is encoded by the human ITGA5 gene. This protein plays a role in cell-matrix adhesion.
National Institutes of Health

Related topics

Related topics

11 relations
Cell AdhesionClusters of differentiationFocal adhesion pathwayGlycoproteins

Broader (1)

Integrin alpha5

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
miR-128 modulates hepatocellular carcinoma by inhibition of ITGA2 and ITGA5 expression.
Dysregulation of miRNAs is a common feature in human cancers, but this phenomenon has not been studied extensively in… 
Review
2008
Review
2008
The Evolving Transcriptome of Head and Neck Squamous Cell Carcinoma: A Systematic Review
Background Numerous studies were performed to illuminate mechanisms of tumorigenesis and metastases from gene expression profiles… 
2007
2007
Uterine Stretch Regulates Temporal and Spatial Expression of Fibronectin Protein and Its Alpha 5 Integrin Receptor in Myometrium of Unilaterally Pregnant Rats1
Abstract The adaptive growth of the uterus during pregnancy is a critical event that involves increased synthesis of… 
2004
2004
Cooperation of syndecan-2 and syndecan-4 among cell surface heparan sulfate proteoglycans in the actin cytoskeletal organization of Lewis lung carcinoma cells.
Syndecan-2 cooperates with integrin alpha 5 beta 1 in cell adhesion to a fibronectin substratum and regulates actin cytoskeletal… 
2002
2002
Biochemical engineering of the acyl side chain of sialic acids stimulates integrin-dependent adhesion of HL60 cells to fibronectin
Abstract. Sialylation of glycoproteins and glycolipids plays an important role during development, regeneration and pathogenesis… 
2001
2001
Occurrence of oligosialic acids on integrin alpha 5 subunit and their involvement in cell adhesion to fibronectin.
Integrin alpha(5)beta(1), a major fibronectin receptor, functions in a wide variety of biological phenomena. We have found that… 
Highly Cited
2000
Highly Cited
2000
Talin controls the exit of the integrin alpha 5 beta 1 from an early compartment of the secretory pathway.
Talin is a major cytosolic protein that links the intracellular domains of beta1 and beta3 integrins to the cytoskeleton. It is… 
1998
1998
Overexpression of C-terminal Src Kinase Homologous Kinase Suppresses Activation of Lyn Tyrosine Kinase Required for VLA5-mediated Dami Cell Spreading*
The Csk homologouskinase (Chk), which is co-expressed with C-terminal Src kinase (Csk) in hematopoietic cells, negatively… 
Highly Cited
1993
Highly Cited
1993
Anaerobic control of denitrification in Pseudomonas stutzeri escapes mutagenesis of an fnr-like gene
The synthesis of proteins necessary for the respiratory reduction of nitrate to dinitrogen is induced in most denitrifying… 
1992
1992
Variant choriocarcinoma (BeWo) cells that differ in adhesion and migration on fibronectin display conserved patterns of integrin expression.
Starting from the BeWo choriocarcinoma cell line, two stable variant cell lines (epi and lc) were isolated. Epi cells displayed… 
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