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ITCH gene

Known as: itchy E3 ubiquitin protein ligase, ITCHY E3 UBIQUITIN PROTEIN LIGASE, MOUSE, HOMOLOG OF, AIP4 
 
National Institutes of Health

Papers overview

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Highly Cited
2018
Highly Cited
2018
BackgroundCirc-ITCH is a circRNA generated from several exons of itchy E3 ubiquitin protein ligase (ITCH) and tumor suppressor… Expand
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Highly Cited
2010
Highly Cited
2010
β-Arrestins, originally discovered to desensitize activated G protein-coupled receptors, (aka seven-transmembrane receptors… Expand
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2010
2010
The Bcr-Abl kinase inhibitor imatinib is remarkably effective in chronic myelogenous leukemia (CML), although drug resistance is… Expand
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Highly Cited
2008
Highly Cited
2008
BACKGROUND The regulation of Notch signaling heavily relies on ubiquitination events. Drosophila Su(dx), a member of the HECT… Expand
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Highly Cited
2006
Highly Cited
2006
Deltex (DTX) and AIP4 are the human orthologues of the Drosophila deltex and Suppressor of deltex, which have been genetically… Expand
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2005
2005
Smad7 functions as an intracellular antagonist in transforming growth factor-beta (TGF-beta) signaling. In addition to… Expand
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Highly Cited
2004
Highly Cited
2004
Ubiquitin family peptide modifications regulate the functions and stabilities of many proteins. We have developed an approach for… Expand
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Highly Cited
2004
Highly Cited
2004
Endophilin A1 is an SH3 domain-containing protein functioning in membrane trafficking on the endocytic pathway. We have… Expand
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Highly Cited
2003
Highly Cited
2003
Ubiquitination of the chemokine receptor CXCR4 serves as a targeting signal for lysosomal degradation, but the mechanisms… Expand
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2002
2002
In metazoans, CBL proteins are RING finger type ubiquitin-protein isopeptide (E3) ligases involved in the down-regulation of… Expand
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