ITCH gene

Known as: itchy E3 ubiquitin protein ligase, ITCHY E3 UBIQUITIN PROTEIN LIGASE, MOUSE, HOMOLOG OF, AIP4 
 

Topic mentions per year

Topic mentions per year

1987-2018
051019872018

Papers overview

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Highly Cited
2015
Highly Cited
2015
Circular RNAs with exonic sequences represent a special form of non-coding RNAs, discovered by analyzing a handful of transcribed… (More)
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2015
2015
Noncoding RNAs (ncRNAs) are the dominant product of eukaryotic transcription. These products range from short microRNAs (miRNAs… (More)
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2014
2014
Inhibition of distinct ubiquitin E3 ligases might represent a powerful therapeutic tool. ITCH is a HECT domain-containing E3… (More)
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2011
2011
The Hippo tumor suppressor pathway, originally defined in fruit flies, regulates cellular proliferation and survival and exerts… (More)
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2010
2010
Ubiquitin ligases play an important role in the regulation of the immune system. Absence of Itch E3 ubiquitin ligase in mice has… (More)
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Highly Cited
2008
Highly Cited
2008
Agouti signaling protein (ASIP) functions to regulate pigmentation in mice, while its role in many other animals and in humans… (More)
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2008
2008
BACKGROUND The regulation of Notch signaling heavily relies on ubiquitination events. Drosophila Su(dx), a member of the HECT… (More)
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Highly Cited
2006
Highly Cited
2006
Deltex (DTX) and AIP4 are the human orthologues of the Drosophila deltex and Suppressor of deltex, which have been genetically… (More)
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2006
2006
p63, a protein related to the tumor suppressor p53, is a transcription factor that plays an important role in epidermal… (More)
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Highly Cited
2004
Highly Cited
2004
Ubiquitin family peptide modifications regulate the functions and stabilities of many proteins. We have developed an approach for… (More)
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