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INPP5D wt Allele

Known as: MGC142140, MGC142142, SH2 Containing Inositol Phosphatase, Isoform B Gene 
Human INPP5D wild-type allele is located in the vicinity of 2q37.1 and is approximately 192 kb in length. This allele, which encodes… Expand
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Endocytosis is required for internalization of micronutrients and turnover of membrane components. Endophilin has been assigned… Expand
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Highly Cited
2012
Highly Cited
2012
Mycobacterium tuberculosis (M.tb.) replicates in host macrophages to cause tuberculosis. We have investigated the role of miRNAs… Expand
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Highly Cited
2011
Highly Cited
2011
Cystic Fibrosis (CF) is characterized by a massive proinflammatory phenotype in the lung arising from profound expression of… Expand
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Highly Cited
2010
Highly Cited
2010
The inositol phosphatase SHIP1 binds to a receptor-adaptor complex on osteoclasts to prevent recruitment of PI3K and inhibit… Expand
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Highly Cited
2007
Highly Cited
2007
Proper neutrophil migration into inflammatory sites ensures host defense without tissue damage. Phosphoinositide 3-kinase (PI(3)K… Expand
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Highly Cited
2007
Highly Cited
2007
Because phosphoinositide 3-kinase (PI3K) plays a central role in cellular activation, proliferation, and survival, pharmacologic… Expand
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Highly Cited
2007
Highly Cited
2007
New studies reveal the dynamic accumulation of phosphatidylinositol (3,4,5) trisphosphate (PtdIns(3,4,5)P3) at the leading edge… Expand
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Review
2006
Review
2006
Cell activation results from the transient displacement of an active balance between positive and negative signaling. This… Expand
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Highly Cited
2005
Highly Cited
2005
Src homology 2 (SH2) domain-containing inositol-5-phosphatase 1 (SHIP1) plays important roles in negatively regulating the… Expand
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Highly Cited
2003
Highly Cited
2003
It has been established that amelioration of murine immune thrombocytopenia purpura (ITP) by IVIg is dependent on the inhibitory… Expand
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