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INPP5D wt Allele

Known as: MGC142140, MGC142142, SH2 Containing Inositol Phosphatase, Isoform B Gene 
Human INPP5D wild-type allele is located in the vicinity of 2q37.1 and is approximately 192 kb in length. This allele, which encodes… 
National Institutes of Health

Related topics

Related topics

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2q37.1B Cell Receptor Signaling PathwayDephosphorylationHydrolysis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2015
Review
2015
SHIP1 and the negative control of mast cell/basophil activation by supra-optimal antigen concentrations.
2014
2014
Impaired T cell survival promotes mucosal inflammatory disease in SHIP1-deficient mice
T cells have a critical role in immune surveillance at mucosal surfaces. SHIP1−/− mice succumb to mucosal inflammatory disease… 
2012
2012
New insights into Dok-4 PTB domain structure and function.
2011
2011
An ENU-induced mouse mutant of SHIP1 reveals a critical role of the stem cell isoform for suppression of macrophage activation.
In a recessive ENU mutagenesis screen for embryonic lethality, we identified a mouse pedigree with a missense mutation of SHIP1… 
2006
2006
Nonspecific Desensitization, Functional Memory, and the Characteristics of SHIP Phosphorylation following IgE-Mediated Stimulation of Human Basophils1
Previous studies of secretion from basophils have demonstrated the phenomenon called nonspecific desensitization, the ability of… 
Review
2006
Review
2006
SHIP1/2 interaction with tyrosine phosphorylated peptides mimicking an immunoreceptor signalling motif.
2001
2001
Regulation of the Src Homology 2-containing Inositol 5-Phosphatase SHIP1 in HIP1/PDGFβR-transformed Cells*
It has been shown previously that the Huntingtin interacting protein 1 gene (HIP1) was fused to the platelet-derived growth… 
Highly Cited
2000
Highly Cited
2000
The SH2 Inositol 5-Phosphatase Ship1 Is Recruited in an SH2-dependent Manner to the Erythropoietin Receptor*
Ship1 (SH2 inositol 5-phosphatase 1) has been shown to be a target of tyrosine phosphorylation downstream of cytokine and… 
1999
1999
The mouse SHIP2 (Inppl1) gene: complementary DNA, genomic structure, promoter analysis, and gene expression in the embryo and adult mouse.
SHIP2 is a new member of the inositol polyphosphate 5-phosphatase family showing homology to SHIP1. The structure of both enzymes… 
Review
1998
Review
1998
Identification and Characterization of an Essential Family of Inositol Polyphosphate 5-Phosphatases ( INP 51 , INP 52 and INP 53 Gene Products ) in the Yeast Saccharomyces cerevisiae
We recently demonstrated that the S. cerevisiae INP51 locus (YIL002c) encodes an inositol polyphosphate 5-phosphatase. Here we… 
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