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IL1A protein, human

Known as: IL-1 Alpha, Interleukin-1-Alpha, Pro-Interleukin-1-Alpha 
One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. IL-1-alpha, one form of IL-1, is made mainly… 
National Institutes of Health

Related topics

Related topics

26 relations
ApoptosisCell Proliferation Regulatory ProcessCytokine GeneCytokine Network Pathway

Broader (1)

Interleukin-1 alpha

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2008
Review
2008
Induction, function and regulation of IL‐17‐producing T cells
Recent reports have provided convincing evidence that IL‐17‐producing T cells play a key role in the pathogenesis of organ… 
Highly Cited
2005
Highly Cited
2005
Regulation of hepcidin transcription by interleukin-1 and interleukin-6.
Hepcidin is a peptide that regulates iron homeostasis by inhibiting iron absorption by the small intestine and release of iron… 
Highly Cited
2005
Highly Cited
2005
Interleukin-1 Is Responsible for Acute Lung Immunopathology but Increases Survival of Respiratory Influenza Virus Infection
ABSTRACT Interleukin-1α (IL-1α) and IL-1β are proinflammatory cytokines, which induce a plethora of genes and activities by… 
Highly Cited
1999
Highly Cited
1999
Expression and regulation of the human beta-defensins hBD-1 and hBD-2 in intestinal epithelium.
The intestinal epithelium forms a physical barrier to limit access of enteric microbes to the host and contributes to innate host… 
Highly Cited
1995
Highly Cited
1995
Induction of vascular endothelial growth factor expression in synovial fibroblasts by prostaglandin E and interleukin‐1: a potential mechanism for inflammatory angiogenesis
Highly Cited
1994
Highly Cited
1994
Induction of cyclooxygenase-2 by interleukin-1 alpha. Evidence for post-transcriptional regulation.
Prostanoids, produced by diverse cell types, modulate a variety of pathophysiological processes. The rate of prostanoid synthesis… 
Highly Cited
1992
Highly Cited
1992
Macrophage colony-stimulating factor gene expression in vascular cells and in experimental and human atherosclerosis.
The infiltration of monocytes into the vascular wall and their transformation into lipid-laden foam cells characterizes early… 
Highly Cited
1991
Highly Cited
1991
Human interleukin (IL) 1 alpha, murine IL-1 alpha and murine IL-1 beta are transported from blood to brain in the mouse by a shared saturable mechanism.
Interleukins (ILs) 1 alpha and 1 beta are important components of the neuroimmune axis. Recent work has shown that human 125I-IL… 
Highly Cited
1989
Highly Cited
1989
Tumor necrosis factor/cachectin plays a key role in bleomycin-induced pneumopathy and fibrosis
The role of TNF-alpha/cachectin in the pneumopathy elicited by bleomycin has been investigated. After a single intratracheal… 
Highly Cited
1988
Highly Cited
1988
Induction of manganous superoxide dismutase by tumor necrosis factor: possible protective mechanism
Manganous superoxide dismutase (MnSOD) scavenges potentially toxic superoxide radicals produced in the mitochondria. Tumor… 
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