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IFN-Stimulated Gene Factor 3 Complex

Known as: ISGF3 Factor, Interferon Stimulated Gene Factor 3, Transcription Factor ISGF3 
A multimeric complex that functions as a ligand-dependent transcription factor. ISGF3 is assembled in the CYTOPLASM and translocated to the CELL… Expand
National Institutes of Health

Papers overview

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Highly Cited
1999
Highly Cited
1999
Activation of cytosolic phospholipase A(2 )(cPLA(2)) is a prerequisite for the formation of the transcription factor complex… Expand
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Review
1999
Review
1999
  • Markus H. Heim
  • Journal of receptor and signal transduction…
  • 1999
  • Corpus ID: 30161644
The Jak-STAT pathway was originally discovered through the study of interferon induced intracellular signal transduction… Expand
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Highly Cited
1999
Highly Cited
1999
Greater than 95% of all cervical carcinomas have been found to be associated with "high-risk" human papillomavirus (mainly types… Expand
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Highly Cited
1998
Highly Cited
1998
Interferon (IFN) genes are among the earliest transcriptional responses to virus infection of mammalian cells. Although the… Expand
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Highly Cited
1996
Highly Cited
1996
The first STAT-containing transcription factor to be studied, the alpha-interferon-induced ISGF3, is composed of a Stat1:2… Expand
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Highly Cited
1996
Highly Cited
1996
Interferon regulatory factor (IRF)-1 and IRF-2 have been implicated for the virus-induced expression of the interferon-alpha and… Expand
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Highly Cited
1995
Highly Cited
1995
Genes containing the interferon-stimulated response element (ISRE) enhancer have been characterized as transcriptionally… Expand
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Highly Cited
1995
Highly Cited
1995
Many genes induced by type I interferons (IFNs) are also induced by double-stranded (ds)RAN. In this study, we investigated the… Expand
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1995
1995
Steel factor (SLF) synergizes with interferon gamma (IFN gamma) to stimulate proliferation of the human factor-dependent cell… Expand
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1993
1993
Infection of cells with adenovirus or transfection of cells with double-stranded RNA (dsRNA) activates transcription of the alpha… Expand
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