IFN-Stimulated Gene Factor 3 Complex

Known as: ISGF3 Factor, Interferon Stimulated Gene Factor 3, Transcription Factor ISGF3 
A multimeric complex that functions as a ligand-dependent transcription factor. ISGF3 is assembled in the CYTOPLASM and translocated to the CELL… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1989-2017
02419892017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Airway epithelial cells are key initial innate immune responders in the fight against respiratory viruses, primarily via the… (More)
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Activation of cytosolic phospholipase A(2 )(cPLA(2)) is a prerequisite for the formation of the transcription factor complex… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Interferon (IFN) genes are among the earliest transcriptional responses to virus infection of mammalian cells. Although the… (More)
  • figure 1
  • table I
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
1996
1996
Interferon regulatory factor (IRF)-1 and IRF-2 have been implicated for the virus-induced expression of the interferon-alpha and… (More)
Is this relevant?
1996
1996
The first STAT-containing transcription factor to be studied, the alpha-interferon-induced ISGF3, is composed of a Stat1:2… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
1995
1995
Genes containing the interferon-stimulated response element (ISRE) enhancer have been characterized as transcriptionally… (More)
Is this relevant?
1995
1995
Many genes induced by type I interferons (IFNs) are also induced by double-stranded (ds)RAN. In this study, we investigated the… (More)
Is this relevant?
1994
1994
Cytokines and growth factors elicit responses in target cells through induction of gene expression. Signaling mechanisms leading… (More)
Is this relevant?
Highly Cited
1993
Highly Cited
1993
Mutants in complementation group U3, completely defective in the response of all genes tested to interferons (IFNs) alpha and… (More)
Is this relevant?
1989
1989
Transcriptional regulation of the gene encoding a guanylate-binding protein (GBP) by the two interferon (IFN) types was studied… (More)
Is this relevant?