IDH2 gene

Known as: ISOCITRATE DEHYDROGENASE, NADP(+)-SPECIFIC, MITOCHONDRIAL, IDPM, isocitrate dehydrogenase 2 (NADP+), mitochondrial 
This gene plays a role in intermediary metabolism.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Mutations in isocitrate dehydrogenase 1 (IDH1) and isocitrate dehydrogenase 2 (IDH2) occur in most grade 2 and 3 gliomas… (More)
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Highly Cited
2011
Highly Cited
2011
Ollier disease and Maffucci syndrome are non-hereditary skeletal disorders characterized by multiple enchondromas (Ollier disease… (More)
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Highly Cited
2010
Highly Cited
2010
PURPOSE To analyze the frequency and associations with prognostic markers and outcome of mutations in IDH genes encoding… (More)
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Highly Cited
2010
Highly Cited
2010
PURPOSE To analyze the frequency and prognostic impact of isocitrate dehydrogenase 1 (IDH1) and isocitrate dehydrogenase 2 (IDH2… (More)
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Highly Cited
2010
Highly Cited
2010
Somatic mutations in isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) were recently demonstrated in acute myeloid leukemia (AML… (More)
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Highly Cited
2010
Highly Cited
2010
Bone marrow DNA was screened for isocitrate dehydrogenase (IDH) mutations in 200 patients with chronic (n=166) or blast (n=34… (More)
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Highly Cited
2010
Highly Cited
2010
Mutations in the nicotinamide adenine dinucleotide phosphate(+)-dependent isocitrate dehydrogenase gene 2 (IDH2) have recently… (More)
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Highly Cited
2009
Highly Cited
2009
Somatic mutations in the IDH1 gene encoding cytosolic NADP+-dependent isocitrate dehydrogenase have been shown in the majority of… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND A recent genomewide mutational analysis of glioblastomas (World Health Organization [WHO] grade IV glioma) revealed… (More)
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Highly Cited
2009
Highly Cited
2009
A recent study reported on mutations in the active site of the isocitrate dehydrogenase 1 (IDH1) gene in several types of gliomas… (More)
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