Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 237,159,866 papers from all fields of science
Search
Sign In
Create Free Account
IDH2 gene
Known as:
ISOCITRATE DEHYDROGENASE, NADP(+)-SPECIFIC, MITOCHONDRIAL
, IDPM
, isocitrate dehydrogenase 2 (NADP+), mitochondrial
Expand
This gene plays a role in intermediary metabolism.
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
11 relations
Astrocytoma
Glioblastoma, IDH-Mutant
IDH1 gene
IDH2 Gene Mutation
Expand
Narrower (1)
IDH2 wt Allele
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
IDH1 and IDH2 : Founding or Progressor Mutations in Myeloid Neoplasms
Wanlong Ma
,
Ivan de Dios
,
+6 authors
M. Albitar
2017
Corpus ID: 201187915
IDH1/2 genes normally regulate cellular metabolism and epigenetic expression. Mutations in IDH1/2 are believed to play a…
Expand
2014
2014
Abstract 963: IDH2(R140Q) knock-in mouse recapitulating human type II D-2-hydroxyglutaric aciduria
F. Wang
,
J. Travins
,
+8 authors
Shengfang Jin
2014
Corpus ID: 57935004
A single amino acid substitution, R140Q, in isocitrate dehydrogenase 2 (IDH2) confers a novel enzymatic activity that converts…
Expand
2014
2014
INK 4 a Impairs Homologous Recombination – Mediated DNA Repair in Human Papillomavirus – Positive Head and Neck Tumors
uveyda Dok
,
Peter Kalev
,
+6 authors
S. Nuyts
2014
Corpus ID: 18513384
The p16INK4a protein is a principal cyclin-dependent kinase inhibitor that decelerates the cell cycle. Abnormally high levels of…
Expand
2014
2014
Impacto de las alteraciones moleculares en el pronóstico de la Leucemia Mieloide Aguda (LMA) "de novo"
M. Colell
2014
Corpus ID: 160196055
La Leucemia Mieloide Aguda (LMA) es una enfermedad hematologica heterogenea, que se caracteriza por la acumulacion de celulas…
Expand
2013
2013
MRS study of metabolic correlation in IDH 1 vs . IDH 2 mutated gliomas
Changho Choi
,
S. Ganji
,
A. Madan
,
Zhongxu An
,
E. Maher
2013
Corpus ID: 46664247
Target audience: Neuro-oncologists/-radiologists, and MR spectroscopists in brain tumors. Purpose: A high fraction of gliomas…
Expand
2012
2012
SIRT3 Deacetylates Isocitrate Dehydrogenase 2 (IDH2) and Regulates Mitochondrial Redox Status
Wei Yu
,
Kristin E. Dittenhafer-Reed
,
J. Denu
2012
Corpus ID: 30603698
Background: NAD + -dependent deacetylase SIRT3 is essential for the prevention of age-related hearing loss during caloric…
Expand
2012
2012
Epigenetics: Melanoma insights written in the DNA
D. Burgess
Nature Reviews. Cancer
2012
Corpus ID: 32982239
A new study shows that disruptions to a DNA modification in melanoma may hold diagnostic and therapeutic promise.
Review
2010
Review
2010
Author's response to reviews Title: Combined mutations of asxl1, cbl, flt3, idh1, idh2, jak2, kras, npm1, nras, runx1, tet2 and wt1 genes in myelodysplastic syndromes and acute myeloid leukemias
J. Rocquain
,
N. Carbuccia
,
V. Trouplin
,
S. Raynaud
,
S. Olschwang
2010
Corpus ID: 16131240
Julien Rocquain (rocquainju@marseille.fnclcc.fr) Nadine Carbuccia (carbuccian@marseille.fnclcc.fr) Virginie Trouplin (trouplinv…
Expand
2010
2010
Prognostic and predictive markers in recurrent high-grade glioma (HGG): Results from the BR12 randomized trial.
M. Brada
,
V. Collins
,
K. Ichimura
,
L. Thompson
,
R. Gabe
,
S. Stenning
2010
Corpus ID: 58991931
2035 Background: BR12 randomised 447 chemo-naive pts with recurrent HGG between PCV and TMZ, subrandomising TMZ between 200 mg/m2…
Expand
1990
1990
Inheritance of isozyme variants and their linkage relationships in Chinese fir (Cunninghamia lanceolata Hook.)
T. Geburek
,
Qihe Wang
Euphytica
1990
Corpus ID: 362698
Summary49 single-clone seed samples of Chinese fir (Cunninghamia lanceolata) were used to investigate genetic variation for nine…
Expand